Objective: The aim of the present study is to assess the role of the level of change in gene expression of the HOTAIR molecule in breast cancer patients. Methods: An assay was conducted for the level of gene expression of the HOTAIR molecule in the plasma of 30 patients and 10 healthy controls, by performing the reverse transcription reaction RT-qPCR, gene expression was evaluated using the Livak equation, tumor characteristics (grade, HER2 receptors, hormonal (...

Cell Biology  Oncology  Biochemistry 

The Cognitive Resonance Theory (CRT) offers a novel theoretical framework for examining the complex interactions between algorithmic personalization, emotional engagement, and the formation of echo chambers within digital media environments. The primary aim of this study is to conceptualize and position CRT as a comprehensive framework for understanding how algorithmic personalization and emotional engagement contribute to echo chambers and societal polarization. This study employs a theoretical...

Sociology  Psychology 

With the in-depth application of ecological theories in the field of educational research, an increasing number of studies have begun to explore classroom teaching practices and the construction of educational ecosystems based on ecological perspectives. The purpose of this paper is to analyze the challenges encountered in the practice of English ecological classroom against the background of the current imbalance of the educational ecosystem, and to propose solutions accordingly, so as to provi...

Language Education 

Progressive ischemic stroke (PIS) is a severe neurological condition with high disability and mortality rates, significantly increasing the economic burden on patients and healthcare systems. It also exacerbates doctor-patient tensions, potentially leading to medical disputes. This retrospective study analyzed 210 cases from the Advanced Stroke Center of the Second Affiliated Hospital of Qiqihar Medical University, comparing PIS patients with general ischemic stroke patients. The results showed ...

Health Policy 

In this article, our focus lies on a Schrödinger equation incorporating a Hardy term. To identify the global minimizers of the functional I under a mass constraint, we utilize the Hardy inequality. In addition, we reveal that every energy ground state is directly linked to the least action solution of the associated action functional. This finding affirmatively addresses the question of whether, under broad assumptions, The functional&...

Functional Analysis 

As a cornerstone of China’s economic modernization, Zhejiang Province has developed a globally influential network of professional markets since its post-reform industrialization. These markets have played a key role in driving local economic growth. This study examines the structural impact of internet-driven innovation on Zhejiang’s markets through three main dimensions: transaction cost reduction, industrial agglomeration, and digital eco-system evolution. The study also suggests policy recom...

Big Data Search and Mining 

Language teachers play a vital role in language education, directly impacting the quality of language learning for students at the basic education stage. This study delves into the analysis of the teacher training system in England, the current status of language teachers in primary and secondary schools, as well as the challenges they face. Following this, it provides reflections on these issues and presents specific recommendations, aiming to foster the continuous development of the language t...

Language Education 

In international relations, the role of media public opinion dissemination is not only the transmission of information, but also the carrier of power games and ideological competition. As a highly sensitive geopolitical issue, the dissemination of public opinion on the South China Sea not only influences the policy choices of countries inside and outside the region, but also profoundly shapes the international community’s perception and attitude towards the South China Sea issue. As important pa...

Sociology  Politics 

Social conflict is inevitable, and everyone has the right to state justice. For the rule of law to be established in a society, one of the essential prerequisites is effective access to justice. There is a distinction between “access to justice” and “justice.” It is sometimes claimed that “access to justice” is the route to “justice,” which is the end in itself. In a narrow sense, the access to justice means access to litigation. Article 27 of our Constitution provides for a fundamental right th...

Sociology  Law 

Political terminology constitutes codified expressions that convey institutional ideologies in diplomatic discourse. This study examines the English translation of key political terms from the 20th National Congress Report through the lens of Hu Gengshen’s Eco-translatology. Adopting textual analysis and comparative assessment methodologies, the research identifies three adaptive translation strategies: linguistic functional equivalence, cultural conceptual mediation, and communicative discourse...

Linguistics