Depressive disorders are complex, multifactorial conditions that exhibit significant variability in treatment response, often influenced by gender differences. This study leverages advanced machine learning (ML) techniques to predict antidepressant response to sertraline and imipramine, addressing the pressing need for personalized treatment strategies. By employing the Synthetic Minority Oversampling Technique (SMOTE), the research overcomes class imbalance—a common limitation in clinical datas...

Artificial Intelligence  Psychiatry & Psychology  Computer Engineering 

Uncontrolled type 1 diabetes mellitus (T1DM) can lead to complications, including hepatic glycogenic overload, also known as Mauriac syndrome. This syndrome, initially described in children with T1DM, is characterized by excessive hepatic glycogen accumulation due to fluctuating hyperglycemia and high insulin doses. It is often underdiagnosed due to clinical overlap with metabolic dysfunction-associated steatotic liver disease (MASLD). We report the case of a 15-year-old boy with poorly controll...

Gastroenterology & Hepatology  Radiology & Medical Imaging  Internal Medicine 

Pneumonia remains a significant cause of morbidity and mortality worldwide, particularly in vulnerable populations such as children and the elderly. Early detection through chest X-ray analysis plays a crucial role in timely treatment; however, reliance on radiologists can lead to variability, delays, and diagnostic errors. This paper presents a convolutional neural network (CNN) designed to automate pneumonia diagnosis from chest X-ray images, addressing the need for faster and more consistent ...

Artificial Intelligence  Diagnostics 

Background: Renal metastases from non-small cell lung cancer (NSCLC) are rare, treatment guidelines for renal metastases from NSCLC are unclear, mostly based on clinical case reports. Data on the effectiveness of osimertinib in the group of patients with renal metastatic NSCLC who have epidermal growth factor receptor (EGFR) mutations del19 or L858R is still incomplete. Purpose: In this study, we report a case of the bilateral renal metastatic NSCLC who was treated by the first...

Oncology 

Letter to the Editor.

Orthopedics 

This paper focuses on the innovative integration of local red cultural resources into college English teaching, taking Shaoxing as a case study. As an important base for revolutionary struggles, Shaoxing has accumulated a rich revolutionary history and culture. The research shows that incorporating this unique cultural heritage into the English curriculum not only enhances students’ language skills but also strengthens their sense of national pride and historical consciousness. Through field vis...

Culture  Language Education 

The potential impact of capital structure on firm performance has gained considerable interest from many researchers and practitioners in the corporate finance field. The interest in capital structure decision stems from its critical impact on firm performance and shareholder wealth. The aim of this study is to examine the impact of capital structure on firm performance in Egypt. For this purpose, this study uses a sample of 40 companies listed on the Egyptian stock exchange during the period fr...

Finance 

This article discusses northern Ghanaian traditional government ideas. These civilizations were under colonial chieftaincy. The goal is to analyze these systems’ democratic qualities and their potential to inform Ghana’s Westminster-based democracy. In Ghana’s Upper East and Upper West regions, the Boosi village of Bongo and the Dagara community of Nandom were investigated. The study used Transcendentalist-inspired qualitative research. This ethnographic study used literature reviews, focus grou...

Culture 

Parental refusal of vaccines is a growing concern for the increased occurrence of vaccine-preventable diseases in children. Many studies have been conducted across the globe about why parents hesitate and are reluctant to vaccinate their children. The reasons for hesitancy vary among parents; studies have shown that there are 4 main reasons for hesitancy. These 4 categories are religious reasons, some personal thoughts, concerns about the safety of the vaccines, and the majority of the parents w...

Allergy & Clinical Immunology 

The textile and clothing manufacturing industry is undergoing rapid technological advancements in areas such as digital sustainability. However, a shortage of high-skilled talent is emerging, particularly in areas like digitizing factories, improving supply chains, implementing resource efficiency strategies, and managing international markets. Workers must not only have traditional textile skills but also cross-sectorial knowledge to support emerging technical textile markets. Vocational educat...

Mechanical Engineering