OALib 期刊
  OALib Journal (ISSN Print: 2333-9705, ISSN Online: 2333-9721)是一本多合一的开源期刊,以同行评审的方式出版发行文章,其所涵盖的研究领域多达311种领域。本刊发表的全部文章均可在期刊网站上免费阅读、下载、引用和传播。单篇文章出版费用为99美元。详情请咨询[email protected] 或 QQ: 3279437679 WhatsApp +8615387084133。现在就去投稿!
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Feb 21, 2025Open    Access

A Comparative Analysis of Machine Learning Models for Real-Time IoT Threat Detection with Focus on Mirai Botnet

Muhammad Mamman Kontagora,Steve A. Adeshina,Habiba Musa
This study presents a comprehensive comparative analysis of machine learning models for real-time detection of Mirai botnet attacks in IoT networks. With the proliferation of IoT devices expected to reach 75 billion by 2025, the need for robust security solutions is critical, especially given the estimated $100 billion in annual global damages from IoT security breaches. We evaluated four machine learning models—Logistic Regression, Random Forest, Gradient Boosting, and Support Vector Machine—us...
Open Access Library J.   Vol.12, 2025
Doi:10.4236/oalib.1112855


Feb 21, 2025Open    Access

Fertilizer Mixing Device for Fertigation System Integrated with Home Assistant Platform

Azrul Mahfurdz,Zainora Kamal Ludin,Suhardi Che Ahmad
Fertigation is becoming increasingly popular among farmers as it ensures consistent and adequate nutrition for each plant. Typically, type A and B fertilizers are mixed manually to achieve the desired EC value, which requires considerable effort from the farmer. In addition, the EC value of the fertilizer mixture varies based on the plant type and growth rate. This is what makes an automatic fertilizer mixing system highly desirable. This project aims to develop an integrated automatic fertilize...
Open Access Library J.   Vol.12, 2025
Doi:10.4236/oalib.1112917


Feb 20, 2025Open    Access

The Complementary Roles of CXCR4 and CXCR7 in Melanoma Migration

Roland Lacap,Nikolas Yousefi,Samantha Hain,Natalie Dahan,Tyler Tran,Justina Gorgy,Ronelle Caguioa,Cindy S. Malone,Ravinder Abrol,Maria Elena de Bellard
The two known receptors, CXCR4 and CXCR7, for the chemokine stromal cell-derived factor-1 (SDF1) play a role in the development and metastasis of multiple cancers, including melanoma. CXCR4 receptor signaling influences melanoma cell responses, including proliferation, migration, and metastasis. CXCR7 receptor signaling can also induce melanoma malignancy by increasing proliferation. However, it is unknown if CXCR7 directly affects melanoma cell migration. Here, we blocked CXCR4 and CXCR7 recept...
Open Access Library J.   Vol.12, 2025
Doi:10.4236/oalib.1112617


Feb 20, 2025Open    Access

Government Coordination in Flood Management in Serang Regency Banten Province Indonesia

Fernandes Simangunsong,Imelda Hutasoit,Manuel Walker Parsaoran Gultom
This study aims to determine and analyze government coordination in flood management, determine and analyze the supporting and inhibiting factors of government coordination in flood management, and determine and analyze efforts to overcome the inhibiting factors of government coordination in flood management in Serang Regency, Banten Province. This study uses the coordination theory proposed by George R. Terry in Erliana Hasan and Eva Eviany (2014) as an analytic tool, which contains seven sub-t...
Open Access Library J.   Vol.12, 2025
Doi:10.4236/oalib.1112334


Feb 19, 2025Open    Access

BDNF Gene Therapy: A Potential Solution for Neurodegenerative Diseases

Tanish Katkar
The research article explores the therapeutic potential of Brain-Derived Neurotrophic Factor (BDNF) gene therapy for Alzheimer’s Disease (AD). AD is characterized by neurofibrillary tangles and amyloid-beta plaques, which contribute to neuronal degradation and cognitive decline. BDNF plays a crucial role in neuronal survival, growth, synaptic plasticity, and cognitive functions like learning and memory. AD patients exhibit reduced BDNF levels, particularly in the cortex and hippocampus. BDNF gen...
Open Access Library J.   Vol.12, 2025
Doi:10.4236/oalib.1112714


Feb 19, 2025Open    Access

The Impact of Job Stress and Work-Life Balance among Indian Nurses: A Correlational Study

Juhee Yadav
The study aims to explore and see the effect of work-related stress/job stress on the Work Life Balance of nurses. The rationale of this study is to analyse the relationship between job stress and Work Life Balance among Indian nurses. The study tries to find out whether high job stress is leading to low work-life balance among Indian Nurses. A total of 163 nurses consisting of 74% females and 27% males and the age group of 20 - 68 years was selected. For this study, all the participants were as...
Open Access Library J.   Vol.12, 2025
Doi:10.4236/oalib.1112841


Feb 19, 2025Open    Access

Multi-Resistant Lymph Node Tuberculosis: A Case Reported in the Lomami Province in the Democratic Republic of the Congo

Theddy Kazadi Kabeya,Dieudonné Mutombo Nsomue,Célestin Katako Lwayo,Sylvain Mbayi Wa Mpata,Jean Muembo Muembo,Ruben Mutamba Mutondo
Drug-resistant tuberculosis is a major challenge for the World Health Organisation (WHO). The emergence of multi-drug resistant tuberculosis is becoming increasingly apparent in Lomami hospitals. However, until now the forms reported have been pulmonary. We report here a case of multidrug-resistant extra-pulmonary tuberculosis (EPTB), the lymph node form. The case was diagnosed at the Kabinda General Referral Hospital (GRH). This case is reported to draw the attention of clinicians to the diagno...
Open Access Library J.   Vol.12, 2025
Doi:10.4236/oalib.1112852


Feb 19, 2025Open    Access

Predicting Bipolar Disorder Treatment Outcomes with Machine Learning: A Comprehensive Evaluation of Random Forest, Gradient Boosting, and Ensemble Approaches

Rocco de Filippis,Abdullah Al Foysal
Accurate prediction of treatment response in bipolar disorder patients with comorbid obsessive-compulsive disorder (OCD) is essential to improving clinical outcomes and minimizing ineffective interventions. The complex interplay between bipolar disorder and OCD often complicates pharmacological treatment, leading to inconsistent results. This study aims to leverage machine learning (ML) techniques to develop predictive models that enhance the precision of quetiapine monotherapy outcomes. The pri...
Open Access Library J.   Vol.12, 2025
Doi:10.4236/oalib.1112897


Feb 19, 2025Open    Access

Case Report: Beneficial Effect of Quetiapine Monotherapy in Bipolar Depression with Comorbid Obsessive-Compulsive Disorder (OCD)

Rocco de Filippis,Abdullah Al Foysal
Bipolar disorder (BD) and obsessive-compulsive disorder (OCD) frequently co-occur, presenting complex clinical challenges that often compromise treatment outcomes. This case report highlights the beneficial effects of quetiapine monotherapy in a 30-year-old female patient diagnosed with bipolar depression and comorbid OCD. Traditional selective serotonin reuptake inhibitors (SSRIs), the first-line treatment for OCD, can induce manic episodes in bipolar patients, necessitating alternative approac...
Open Access Library J.   Vol.12, 2025
Doi:10.4236/oalib.1112898


Feb 19, 2025Open    Access

Radiocarpal Dislocation Associated with Enucleation of the Semilunar: A Clinical Case Report

Malick Diop,Mohamed Hachim,Ousmane Ba,Ibrahima S. Camara,Mayoro Sow,Mohamed Daffé
Introduction: The association of radiocarpal dislocation with enucleation of the semilunate remains a rare injury. It often occurs following violent trauma. Observation: A 25-year-old right-handed patient presented with open trauma to the left hand and wrist. His hand had been forcibly trapped by a car door. Examination revealed a linear wound on the dorsal surface of the hand and a wound on the anterior surface of the wrist. Active bleeding along the radial art...
Open Access Library J.   Vol.12, 2025
Doi:10.4236/oalib.1112928


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