Elderly individuals undergoing long-term neuroleptic therapy are increasingly vulnerable to cognitive decline, a condition that significantly impairs quality of life and increases healthcare burden. One contributing factor is the cumulative anticholinergic burden from prescribed antipsychotic medications. This study aims to explore the relationship between anticholinergic load and cognitive impairment in aging patients using an interpretable machine learning framework. We developed a synthetic d...

Psychiatry & Psychology 

Managing psychiatric disorders, including depression, anxiety, and bipolar disorder, during pregnancy presents significant clinical challenges due to uncertainties surrounding medication safety and efficacy for both the mother and fetus. This study introduces a novel deep learning (DL)-based decision-support framework aimed at personalizing pharmacotherapy for pregnant patients diagnosed with psychiatric conditions. By leveraging electronic health records (EHRs), pharmacogenomic data, and advanc...

Psychiatry & Psychology 

Introduction: Pregnancy-induced hypertension (PIH) is a significant cause of morbidity and mortality among expectant mothers. While some women may be unaware of its existence, others hold misconceptions about its nature or attribute symptoms to superstitions. This study aimed to assess the prevalence, risk factors, and complications of pregnancy-related hypertension among women at Tamale Teaching Hospital. Methods: This cross-sectional study utilized hospital re...

Gynecology & Obstetrics 

Despite Parkinson’s Disease (PD) typically being diagnosed after 80% of dopaminergic neurons are lost, evidence suggests that many patients exhibit early symptoms and frequently utilize emergency department (ED) services years before formal diagnosis. Here we examine the untapped potential of EDs in early PD recognition and intervention. Analysis of nearly 14,000 PD patients from two major healthcare systems revealed that 74% visited the ED or urgent care in the two years preceding diagnosis, ye...

Public Health  Emergency & Critical Care  Neurology 

The relationship between chance and determinism has been analyzed by philosophy, mathematics, and physics. With the aim of identifying the intersection between the two, the Law of Probability Equilibrium (LPE) was demonstrated. When the probabilities of natural phenomena differ from zero and one, the LPE shows that the observed probability is empirical and that the cumulative probability functions of these phenomena measure the imminence of their occurrence (“energy concentration”). These functi...

Atomic Physics 

Employees increasingly use social media to showcase achievements, but this self-presentation may unintentionally provoke envy among peers. While past studies have examined workplace envy in offline settings, little research explores how active self-promotion (e.g., posting accomplishments) and passive browsing (e.g., viewing others’ posts) on platforms like LinkedIn, Face-book, or Instagram contribute to envy. Additionally, the role of workplace friendships in reducing this effect remains unclea...

Business Management  Business Communication  Business Analysis 

The advent of the internet, as we all know, has brought about a significant change in human interaction and business operations around the world; yet, this evolution has also been marked by security issues, including phishing attacks that represent one of the biggest problems to internet users, leading to financial loss and identity theft. The ability of Machine learning and ensemble learning models to process large datasets and complex relationships, and to learn from data have made it easier t...

Network Modeling and Simulation 

Biliary acute pancreatitis (BAP) is a frequent and potentially severe condition requiring appropriate and timely management to reduce complications and recurrence. This study reviews the clinical characteristics and therapeutic approaches to BAP, with a particular focus on the timing of cholecystectomy. The analysis highlights a discrepancy between current international guidelines, which recommend performing cholecystectomy during the same hospitalization, and real-life practices in a regional h...

Gastroenterology & Hepatology 

Introduction: Peer learning is an asset that contributes to improving the acquisition of knowledge and skills development among students of the Higher Institute of Medical Techniques of Lubumbashi based on the experiences of peers. The objective of this study is to evaluate the usefulness of peer learning on the behavior of students at the Institut Supérieur des Techniques Médicales in Lubumbashi, DR Congo. Method: We conducted a cross-sectional descriptive stud...

Educational Reform 

With the acceleration of globalization, the tourism industry is experiencing unprecedented rapid development. However, language barriers and cultural differences have become key factors restricting the further development of the tourism industry. The concept of smart tourism provides new ideas and methods to solve these problems. This paper aims to deeply explore the multilingual application and value of smart tourism, analyze the current problems, and propose innovative application strategies, ...

Sociology  Language Education