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Arthritis Research & Therapy

ISSN Print: 1478-6354

ISSN Online:

主页: http://arthritis-research.com

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Developments in the scientific understanding of lupus

Stacy P Ardoin, David S Pisetsky

Reduced proportions of natural killer T cells are present in the relatives of lupus patients and are associated with autoimmunity

Joan Wither, Yong-chun Cai, Sooyeol Lim, Tamara McKenzie, Nicole Roslin, Jaime O Claudio, Glinda S Cooper, Thomas J Hudson, Andrew D Paterson, Celia MT Greenwood, Dafna Gladman, Janet Pope, Christian A Pineau, C Douglas Smith, John G Hanly, Christine Peschken, Gilles Boire, CaNIOS Investigators, Paul R Fortin

A meta-analysis of the efficacy of fibromyalgia treatment according to level of care

Javier Garcia-Campayo, Jesus Magdalena, Rosa Magallón, Esther Fernández-García, Montserrat Salas, Eva Andrés

Characteristics of repair tissue in second-look and third-look biopsies from patients treated with engineered cartilage: relationship to symptomatology and time after implantation

Paola Brun, Sally C Dickinson, Barbara Zavan, Roberta Cortivo, Anthony P Hollander, Giovanni Abatangelo

High avidity autoreactive T cells with a low signalling capacity through the T-cell receptor: central to rheumatoid arthritis pathogenesis?

Ranjeny Thomas, Malcolm Turner, Andrew P Cope

High-density lipoprotein: does it have a dark side?

Joan M Von Feldt

Fibromyalgia and sleep-disordered breathing: the missing link – author's response

Jean Eisinger

Vascular involvement in rheumatic diseases: 'vascular rheumatology'

Zoltán Szekanecz, Alisa E Koch

Lipooxygenase inhibition in osteoarthritis: a potential symptomatic and disease modifying effect?

Maxime Dougados

Molecular discrimination of responders and nonresponders to anti-TNFalpha therapy in rheumatoid arthritis by etanercept

Dirk Koczan, Susanne Drynda, Michael Hecker, Andreas Drynda, Reinhard Guthke, Joern Kekow, Hans-Juergen Thiesen

Epitope spreading to citrullinated antigens in mouse models of autoimmune arthritis and demyelination

Brian A Kidd, Peggy P Ho, Orr Sharpe, Xiaoyan Zhao, Beren H Tomooka, Jennifer L Kanter, Lawrence Steinman, William H Robinson

Toll-like receptor homolog RP105 modulates the antigen-presenting cell function and regulates the development of collagen-induced arthritis

Yoshifumi Tada, Syuichi Koarada, Fumitaka Morito, Mio Mitamura, Hisako Inoue, Rie Suematsu, Akihide Ohta, Kensuke Miyake, Kohei Nagasawa

Monocytes are essential for inhibition of synovial T-cell glucocorticoid-mediated apoptosis in rheumatoid arthritis

Dimitrios Makrygiannakis, Shankar Revu, Petra Nereg？rd, Erik af Klint, Omri Snir, Cecilia Grundtman, Anca Catrina

All-trans retinoic acid suppresses interleukin-6 expression in interleukin-1-stimulated synovial fibroblasts by inhibition of ERK1/2 pathway independently of RAR activation

Mélanie Kirchmeyer, Meriem Koufany, Sylvie Sebillaud, Patrick Netter, Jean-Yves Jouzeau, Arnaud Bianchi

Synergistic role of c-Myc and ERK1/2 in the mitogenic response to TGFβ-1 in cultured rat nucleus pulposus cells

Tomoko Nakai, Joji Mochida, Daisuke Sakai

T-614, a novel immunomodulator, attenuates joint inflammation and articular damage in collagen-induced arthritis

Fang Du, Liang-jing Lü, Qiong Fu, Min Dai, Jia-lin Teng, Wei Fan, Shun-le Chen, Ping Ye, Nan Shen, Xin-fang Huang, Jie Qian, Chun-de Bao

Retinoid X receptor and peroxisome proliferator-activated receptor-gamma agonists cooperate to inhibit matrix metalloproteinase gene expression

Peter S Burrage, Adam C Schmucker, Yanqing Ren, Michael B Sporn, Constance E Brinckerhoff

Fragmentation of decorin, biglycan, lumican and keratocan is elevated in degenerate human meniscus, knee and hip articular cartilages compared with age-matched macroscopically normal and control tissues

James Melrose, Emily S Fuller, Peter J Roughley, Margaret M Smith, Briedgeen Kerr, Clare E Hughes, Bruce Caterson, Christopher B Little

Arthritogenic T cell epitope in glucose-6-phosphate isomerase-induced arthritis

Keiichi Iwanami, Isao Matsumoto, Yoko Tanaka, Asuka Inoue, Daisuke Goto, Satoshi Ito, Akito Tsutsumi, Takayuki Sumida

Cartilage oligomeric matrix protein deficiency promotes early onset and the chronic development of collagen-induced arthritis

Hui Geng, Stefan Carlsen, Kutty Nandakumar, Rikard Holmdahl, Anders Aspberg, ？ke Oldberg, Ragnar Mattsson

Therapeutic efficacy of intra-articular adrenomedullin injection in antigen-induced arthritis in rabbits

Toshiyuki Okura, Kousuke Marutsuka, Hiroaki Hamada, Tomohisa Sekimoto, Tsuyoshi Fukushima, Yujiro Asada, Kazuo Kitamura, Etsuo Chosa

Regulatory T cells in systemic lupus erythematosus: past, present and future

David A Horwitz

Vastus medialis cross-sectional area is positively associated with patella cartilage and bone volumes in a pain-free community-based population

Patricia A Berry, Andrew J Teichtahl, Ana Galevska-Dimitrovska, Fahad S Hanna, Anita E Wluka, Yuanyuan Wang, Donna M Urquhart, Dallas R English, Graham G Giles, Flavia M Cicuttini

Role of STAT4 polymorphisms in systemic lupus erythematosus in a Japanese population: a case-control association study of the STAT1-STAT4 region

Aya Kawasaki, Ikue Ito, Koki Hikami, Jun Ohashi, Taichi Hayashi, Daisuke Goto, Isao Matsumoto, Satoshi Ito, Akito Tsutsumi, Minori Koga, Tadao Arinami, Robert R Graham, Geoffrey Hom, Yoshinari Takasaki, Hiroshi Hashimoto, Timothy W Behrens, Takayuki Sumida, Naoyuki Tsuchiya

Biochemical markers of bone turnover and their association with bone marrow lesions

David J Hunter, Michael LaValley, Jiang Li, Doug C Bauer, Michael Nevitt, Jeroen DeGroot, Robin Poole, David Eyre, Ali Guermazi, Daniel Gale, Saara Totterman, David T Felson

Rationale for prostaglandin I2 in bone marrow oedema – from theory to application

Marcus J？ger, Frank Tillmann, Thomas S Thornhill, Marcus Mahmoudi, Dirk Blondin, Gerd Hetzel, Christoph Zilkens, Rüdiger Krauspe

Therapeutic effect of the potent IL-12/IL-23 inhibitor STA-5326 on experimental autoimmune uveoretinitis

Hiroshi Keino, Takayo Watanabe, Yasuhiko Sato, Mamoru Niikura, Yumiko Wada, Annabelle A Okada

Mapping similarities in mTOR pathway perturbations in mouse lupus nephritis models and human lupus nephritis

Padmalatha S Reddy, Holly M Legault, Joseph P Sypek, Mark J Collins, Elizabeth Goad, Samuel J Goldman, Wei Liu, Stuart Murray, Andrew J Dorner, Margot O'Toole

Raised intrathecal levels of APRIL and BAFF in patients with systemic lupus erythematosus: relationship to neuropsychiatric symptoms

Annie George-Chandy, Estelle Trysberg, Kristina Eriksson

Correction: Association of the FCRL3 gene with rheumatoid arthritis: a further example of population specificity?

Stephen Eyre, John Bowes, Catherine Potter, Jane Worthington, Anne Barton

Elevated autoantibody content in rheumatoid arthritis synovia with lymphoid aggregates and the effect of rituximab

Sanna Rosengren, Nathan Wei, Kenneth C Kalunian, Nathan J Zvaifler, Arthur Kavanaugh, David L Boyle

Antibodies to mutated citrullinated vimentin for diagnosing rheumatoid arthritis in anti-CCP-negative patients and for monitoring infliximab therapy

Pascale Nicaise Roland, Sabine Grootenboer Mignot, Alessandra Bruns, Margarita Hurtado, Elisabeth Palazzo, Gilles Hayem, Philippe Dieudé, Olivier Meyer, Sylvie Chollet Martin

Circulating immune complexes contain citrullinated fibrinogen in rheumatoid arthritis

Xiaoyan Zhao, Nwora Okeke, Orr Sharpe, Franak M Batliwalla, Annette T Lee, Peggy P Ho, Beren H Tomooka, Peter K Gregersen, William H Robinson

Epitope spreading in animal models: array of hope in rheumatoid arthritis and multiple sclerosis

Karin Lundberg, Patrick J Venables

The roles of the classical and alternative nuclear factor-kappaB pathways: potential implications for autoimmunity and rheumatoid arthritis

Keith D Brown, Estefania Claudio, Ulrich Siebenlist

Genetic studies in osteoporosis – the end of the beginning

Emma L Duncan, Matthew A Brown

Increased susceptibility to collagen-induced arthritis in female mice carrying congenic Cia40/Pregq2 fragments

Maria Liljander, ？sa Andersson, Rikard Holmdahl, Ragnar Mattsson

Adipose-derived mesenchymal stem cells from the sand rat: transforming growth factor beta and 3D co-culture with human disc cells stimulate proteoglycan and collagen type I rich extracellular matrix

Hazel Tapp, Ray Deepe, Jane A Ingram, Marshall Kuremsky, Edward N Hanley, Helen E Gruber

Human palatine tonsil: a new potential tissue source of multipotent mesenchymal progenitor cells

Sasa Janjanin, Farida Djouad, Rabie M Shanti, Dolores Baksh, Kiran Gollapudi, Drago Prgomet, Lars Rackwitz, Arjun S Joshi, Rocky S Tuan

Altered fractalkine cleavage results in an organ-specific 17 kDa fractalkine fragment in salivary glands of NOD mice

Nicolas Delaleu, Roland Jonsson

Association of elevated transcript levels of interferon-inducible chemokines with disease activity and organ damage in systemic lupus erythematosus patients

Qiong Fu, Xiaoqing Chen, Huijuan Cui, Yanzhi Guo, Jing Chen, Nan Shen, Chunde Bao

A polymorphism in the human serotonin 5-HT2A receptor gene may protect against systemic sclerosis by reducing platelet aggregation

Lorenzo Beretta, Marta Cossu, Maurizio Marchini, Francesca Cappiello, Andrea Artoni, Giovanna Motta, Raffaella Scorza

Are biologics more effective than classical disease-modifying antirheumatic drugs?

Michael T Nurmohamed, Ben AC Dijkmans

Vitamin D or hormone D deficiency in autoimmune rheumatic diseases, including undifferentiated connective tissue disease

Maurizio Cutolo

Gluten-free vegan diet induces decreased LDL and oxidized LDL levels and raised atheroprotective natural antibodies against phosphorylcholine in patients with rheumatoid arthritis: a randomized study

Ann-Charlotte Elkan, Beatrice Sj？berg, Bj？rn Kolsrud, Bo Ringertz, Ingi？ld Hafstr？m, Johan Frosteg？rd

Faecal blood loss with aspirin, nonsteroidal anti-inflammatory drugs and cyclo-oxygenase-2 selective inhibitors: systematic review of randomized trials using autologous chromium-labelled erythrocytes

R Andrew Moore, Sheena Derry, Henry J McQuay

Identification of novel monosodium urate crystal regulated mRNAs by transcript profiling of dissected murine air pouch membranes

Frank Pessler, Christian T Mayer, Sung Jung, Ed M Behrens, Lie Dai, Joseph P Menetski, H Ralph Schumacher

Incremental cost effectiveness of proton pump inhibitors for the prevention of non-steroidal anti-inflammatory drug ulcers: a pharmacoeconomic analysis linked to a case-control study

Harald E Vonkeman, Louise MA Braakman-Jansen, Rogier M Klok, Maarten J Postma, Jacobus RBJ Brouwers, Mart AFJ van de Laar

Collagen-specific T-cell repertoire in blood and synovial fluid varies with disease activity in early rheumatoid arthritis

Francesco Ria, Romina Penitente, Maria De Santis, Chiara Nicolò, Gabriele Di Sante, Massimiliano Orsini, Dario Arzani, Andrea Fattorossi, Alessandra Battaglia, Gian Ferraccioli

4-Hydroxynonenal induces apoptosis in human osteoarthritic chondrocytes: the protective role of glutathione-S-transferase

France Vaillancourt, Hassan Fahmi, Qin Shi, Patrick Lavigne, Pierre Ranger, Julio C Fernandes, Mohamed Benderdour

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