Modular decomposition of protein-protein interaction networks

Julien Gagneur, Roland Krause, Tewis Bouwmeester, Georg Casari

POSaM: a fast, flexible, open-source, inkjet oligonucleotide synthesizer and microarrayer

Christopher Lausted, Timothy Dahl, Charles Warren, Kimberly King, Kimberly Smith, Michael Johnson, Ramsey Saleem, John Aitchison, Lee Hood, Stephen R Lasky

After 'completion': the changing face of human chromosomes 21 and 22

Todd Taylor

Articles selected by Faculty of 1000: profiling flowers; targeted transgenesis in Drosophila; aging and oxidation in plants; membrane protein localization in E. coli; immune response to siRNAs

The evolving human brain

Melissa Phillips

Nanotubes link immune cells

Charles Choi

Microarray analysis of microRNA expression in the developing mammalian brain

Eric A Miska, Ezequiel Alvarez-Saavedra, Matthew Townsend, Akira Yoshii, Nenad ？estan, Pasko Rakic, Martha Constantine-Paton, H Robert Horvitz

Ploidy predicts lifestyle

Cathy Holding

How worms tackle stress

David Secko

The MAP2/Tau family of microtubule-associated proteins

Leif Dehmelt, Shelley Halpain

Non-coding DNA adapts

Melissa Phillips

Integrating transcriptional controls for plant cell expansion

Keithanne Mockaitis, Mark Estelle

The emperor's new shibboleth

Gregory A Petsko

The ASRG database: identification and survey of Arabidopsis thaliana genes involved in pre-mRNA splicing

Bing-Bing Wang, Volker Brendel

Hotspots of homologous recombination in the human genome: not all homologous sequences are equal

James R Lupski

Getting on top, genetically

Ishani Ganguli

Integration with the human genome of peptide sequences obtained by high-throughput mass spectrometry

Frank Desiere, Eric W Deutsch, Alexey I Nesvizhskii, Parag Mallick, Nichole L King, Jimmy K Eng, Alan Aderem, Rose Boyle, Erich Brunner, Samuel Donohoe, Nelson Fausto, Ernst Hafen, Lee Hood, Michael G Katze, Kathleen A Kennedy, Floyd Kregenow, Hookeun Lee, Biaoyang Lin, Dan Martin, Jeffrey A Ranish, David J Rawlings, Lawrence E Samelson, Yuzuru Shiio, Julian D Watts, Bernd Wollscheid, Michael E Wright, Wei Yan, Lihong Yang, Eugene C Yi, Hui Zhang, Ruedi Aebersold

Computational prediction of human metabolic pathways from the complete human genome

Pedro Romero, Jonathan Wagg, Michelle L Green, Dale Kaiser, Markus Krummenacker, Peter D Karp

Platypus has 10 sex chromosomes

Nick Atkinson

Fungus report stirs debate

Charles Q Choi

Natural selection in humans

Charles Q Choi

Identification of the prokaryotic ligand-gated ion channels and their implications for the mechanisms and origins of animal Cys-loop ion channels

Asba Tasneem, Lakshminarayan M Iyer, Eric Jakobsson, L Aravind

Pokemon's cancer role revealed

Marta Paterlini

Articles selected by Faculty of 1000: a TATA-box binding protein survey; Arabidopsis enzyme-activity profiling; cis-regulatory systems in Ascomycetes; Candida comparative genomics; a functional genomics pipeline

Genome informatics: taming the avalanche of genomic data

Erik LL Sonnhammer

Fish genes work in human cells

Cathy Holding

The 3-hydroxy-3-methylglutaryl coenzyme-A (HMG-CoA) reductases

Jon A Friesen, Victor W Rodwell

The Mammalian Phenotype Ontology as a tool for annotating, analyzing and comparing phenotypic information

Cynthia L Smith, Carroll-Ann W Goldsmith, Janan T Eppig

Microarray-based resequencing of multiple Bacillus anthracis isolates

Michael E Zwick, Farrell Mcafee, David J Cutler, Timothy D Read, Jacques Ravel, Gregory R Bowman, Darrell R Galloway, Alfred Mateczun

MRC gets thumbs up

Robert Walgate

NIH says scientists should share

Peg Brickley

Gut response

Cathy Holding

Tall, skinny, RNAi decaf, to go

Tudor Toma

Live and let diet

Gregory A Petsko

Evolutionary history, structural features and biochemical diversity of the NlpC/P60 superfamily of enzymes

Vivek Anantharaman, L Aravind

Sorting the maize

Tudor Toma

The usual suspects

Gregory A Petsko

Articles selected by Faculty of 1000: archaeal adaptation to cold; human chromosome 7 sequence; comparative protein-structure modeling; new algorithm for sequence alignment; expression profiling human mast cells

EU researches superbugs

Rossella Lorenzi

Articles selected by Faculty of 1000: Pseudomonas putida genome; SAGE analysis of cell death; array analysis of apoptosis; screen for phosphopeptide binding domain; using non-natural amino acids.

Cross-species transfer is last straw

Cathy Holding

MicroRNA Targets in Drosophila

Anton Enright, Bino John, Ulrike Gaul, Thomas Tuschl, Chris Sander, Debora Marks

Caste- and development-associated gene expression in a lower termite

Michael E Scharf, Dancia Wu-Scharf, Barry R Pittendrigh, Gary W Bennett

Gene deserts bear fruit

Cathy Holding

Decoding the epigenetic effects of chromatin

Richard Festenstein, Luis Aragon

Phosphopeptide proteomics

Jonathan B Weitzman

A question of taste

Jonathan B Weitzman

How bacteria induce stomach ulcers

Jonathan Weitzman

Turning back the clock

Jonathan B Weitzman

Ira

Gregory A Petsko