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ISSN: 2333-9721
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Molecular Cancer

ISSN Print: 1476-4598

ISSN Online:

主页: http://www.molecular-cancer.com

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Kinome expression profiling and prognosis of basal breast cancers

Renaud Sabatier, Pascal Finetti, Emilie Mamessier, Stéphane Raynaud, Nathalie Cervera, Eric Lambaudie, Jocelyne Jacquemier, Patrice Viens, Daniel Birnbaum, Fran？ois Bertucci

BMI1 and Mel-18 oppositely regulate carcinogenesis and progression of gastric cancer

Xiao-Wei Zhang, Ya-Ping Sheng, Qian Li, Wei Qin, You-Wei Lu, Yu-Fan Cheng, Bing-Ya Liu, Feng-Chun Zhang, Jin Li, Goberdhan P Dimri, Wei-Jian Guo

Analysis of an alternative human CD133 promoter reveals the implication of Ras/ERK pathway in tumor stem-like hallmarks

Kouichi Tabu, Taichi Kimura, Ken Sasai, Lei Wang, Norihisa Bizen, Hiroshi Nishihara, Tetsuya Taga, Shinya Tanaka

Gene expression in nontumoral liver tissue and recurrence-free survival in hepatitis C virus-positive hepatocellular carcinoma

Masato Tsuchiya, Joel S Parker, Hiroshi Kono, Masanori Matsuda, Hideki Fujii, Ivan Rusyn

Maslinic acid potentiates the anti-tumor activity of tumor necrosis factor α by inhibiting NF-κB signaling pathway

Chenghai Li, Zhengfeng Yang, Chunyan Zhai, Wenwei Qiu, Dali Li, Zhengfang Yi, Lei Wang, Jie Tang, Min Qian, Jian Luo, Mingyao Liu

MicroRNA-101 negatively regulates Ezh2 and its expression is modulated by androgen receptor and HIF-1α/HIF-1β

Paul Cao, Zhiyong Deng, Meimei Wan, Weiwei Huang, Scott D Cramer, Jianfeng Xu, Ming Lei, Guangchao Sui

Carnosine retards tumor growth in vivo in an NIH3T3-HER2/neu mouse model

Christof Renner, Nadine Zemitzsch, Beate Fuchs, Kathrin D Geiger, Matthias Hermes, Jan Hengstler, Rolf Gebhardt, Jürgen Meixensberger, Frank Gaunitz

Sindbis viral vector induced apoptosis requires translational inhibition and signaling through Mcl-1 and Bak

Lisa Venticinque, Daniel Meruelo

Predictive value of progression-related gene classifier in primary non-muscle invasive bladder cancer

Wun-Jae Kim, Eun-Jung Kim, Seon-Kyu Kim, Yong-June Kim, Yun-Sok Ha, Pildu Jeong, Min-Ju Kim, Seok-Joong Yun, Keon Lee, Sung-Kwon Moon, Sang-Cheol Lee, Eun-Jong Cha, Suk-Chul Bae

Epstein-Barr virus-encoded EBNA1 inhibits the canonical NF-κB pathway in carcinoma cells by inhibiting IKK phosphorylation

Robert Valentine, Christopher W Dawson, Chunfang Hu, Khilan M Shah, Thomas J Owen, Kathryn L Date, Sonia P Maia, Jianyong Shao, John R Arrand, Lawrence S Young, John D O'Neil

The Wnt/β-catenin pathway regulates growth and maintenance of colonospheres

Shailender S Kanwar, Yingjie Yu, Jyoti Nautiyal, Bhaumik B Patel, Adhip PN Majumdar

Molecular assays for the detection of prostate tumor derived nucleic acids in peripheral blood

Matthias Jost, John R Day, Ryan Slaughter, Theodore D Koreckij, Deanna Gonzales, Martin Kinnunen, Jack Groskopf, Harry G Rittenhouse, Robert L Vessella, Mark A Reynolds

Dasatinib reverses Cancer-associated Fibroblasts (CAFs) from primary Lung Carcinomas to a Phenotype comparable to that of normal Fibroblasts

Silke Haubeiss, Jens O Schmid, Thomas E Mürdter, Maike Sonnenberg, Godehard Friedel, Heiko van der Kuip, Walter E Aulitzky

Deletion analysis of BMI1 oncoprotein identifies its negative regulatory domain

Ajay K Yadav, Anagh A Sahasrabuddhe, Manjari Dimri, Prashant V Bommi, Rachana Sainger, Goberdhan P Dimri

Cathepsin B inhibition interferes with metastatic potential of human melanoma: an in vitro and in vivo study

Paola Matarrese, Barbara Ascione, Laura Ciarlo, Rosa Vona, Carlo Leonetti, Marco Scarsella, Anna M Mileo, Caterina Catricalà, Marco G Paggi, Walter Malorni

Glycogen synthase kinase 3 beta: can it be a target for oral cancer

Rajakishore Mishra

Polycomb repressor complex 2 regulates HOXA9 and HOXA10, activating ID2 in NK/T-cell lines

Stefan Nagel, Letizia Venturini, Victor E Marquez, Corinna Meyer, Maren Kaufmann, Michaela Scherr, Roderick AF MacLeod, Hans G Drexler

RNAi phenotype profiling of kinases identifies potential therapeutic targets in Ewing's sarcoma

Shilpi Arora, Irma M Gonzales, R Hagelstrom, Christian Beaudry, Ashish Choudhary, Chao Sima, Raoul Tibes, Spyro Mousses, David O Azorsa

A Pleiotrophin C-terminus peptide induces anti-cancer effects through RPTPβ/ζ

Zoi Diamantopoulou, Oya Bermek, Apostolos Polykratis, Yamina Hamma-Kourbali, Jean Delbé, José Courty, Panagiotis Katsoris

Expression of the leukemic prognostic marker CD7 is linked to epigenetic modifications in chronic myeloid leukemia

Sally L Rogers, Yun Zhao, Xiaoyan Jiang, Connie J Eaves, Dixie L Mager, Arefeh Rouhi

A biology-driven approach identifies the hypoxia gene signature as a predictor of the outcome of neuroblastoma patients

Paolo Fardin, Annalisa Barla, Sofia Mosci, Lorenzo Rosasco, Alessandro Verri, Rogier Versteeg, Huib N Caron, Jan J Molenaar, Ingrid ？ra, Alessandra Eva, Maura Puppo, Luigi Varesio

Transcriptional regulation of human osteopontin promoter by histone deacetylase inhibitor, trichostatin A in cervical cancer cells

Priyanka Sharma, Santosh Kumar, Gopal C Kundu

MMP13 mediates cell cycle progression in melanocytes and melanoma cells: in vitro studies of migration and proliferation

Svenja Meierjohann, Anita Hufnagel, Elisabeth Wende, Markus A Kleinschmidt, Katarina Wolf, Peter Friedl, Stefan Gaubatz, Manfred Schartl

Anti-apoptotic role of HIF-1 and AP-1 in paclitaxel exposed breast cancer cells under hypoxia

Lionel Flamant, Annick Notte, Noelle Ninane, Martine Raes, Carine Michiels

PKCα expression is a marker for breast cancer aggressiveness

Gry L？nne, Louise Cornmark, Iris Zahirovic, G？ran Landberg, Karin Jirstr？m, Christer Larsson

Characterization of bortezomib-adapted I-45 mesothelioma cells

Lidong Zhang, James E Littlejohn, Yu Cui, Xiaobo Cao, Chander Peddaboina, W Roy Smythe

Targeting Hsp90 with small molecule inhibitors induces the over-expression of the anti-apoptotic molecule, survivin, in human A549, HONE-1 and HT-29 cancer cells

Chun Hei Antonio Cheung, Huang-Hui Chen, Li-Ting Cheng, Kevin W Lyu, Jagat R Kanwar, Jang-Yang Chang

The anti-aging gene KLOTHO is a novel target for epigenetic silencing in human cervical carcinoma

Jaehyouk Lee, Dong-Jun Jeong, Jinsun Kim, Soonduck Lee, Jin-Hwa Park, Boogi Chang, Sam-Il Jung, Lisha Yi, Youngsoo Han, Young Yang, Keun Kim, Jong-Seok Lim, Inchul Yang, Seob Jeon, Dong Bae, Chang-Jin Kim, Myeong-Sok Lee

Molecular mechanisms of acquired resistance to tyrosine kinase targeted therapy

J Rafael Sierra, Virna Cepero, Silvia Giordano

Integrative and comparative genomics analysis of early hepatocellular carcinoma differentiated from liver regeneration in young and old

Dilek Colak, Muhammad A Chishti, Al-Bandary Al-Bakheet, Ahmed Al-Qahtani, Mohamed M Shoukri, Malcolm H Goyns, Pinar T Ozand, John Quackenbush, Ben H Park, Namik Kaya

Tasquinimod (ABR-215050), a quinoline-3-carboxamide anti-angiogenic agent, modulates the expression of thrombospondin-1 in human prostate tumors

Anders Olsson, Anders Bj？rk, Johan Vallon-Christersson, John T Isaacs, Tomas Leanderson

Smad2 and Smad6 as predictors of overall survival in oral squamous cell carcinoma patients

Flavia RR Mangone, Fernando Walder, Simone Maistro, Fátima S Pasini, Carlos N Lehn, Marcos B Carvalho, M Mitzi Brentani, Igor Snitcovsky, Miriam HH Federico

Identification of non-coding RNAs embracing microRNA-143/145 cluster

Akio Iio, Yoshihito Nakagawa, Ichiro Hirata, Tomoki Naoe, Yukihiro Akao

Enhanced anti-tumor activity of a new curcumin-related compound against melanoma and neuroblastoma cells

Marina Pisano, Gabriella Pagnan, Maria Dettori, Sara Cossu, Irene Caffa, Ilaria Sassu, Laura Emionite, Davide Fabbri, Michele Cilli, Fabio Pastorino, Giuseppe Palmieri, Giovanna Delogu, Mirco Ponzoni, Carla Rozzo

Survival signalling and apoptosis resistance in glioblastomas: opportunities for targeted therapeutics

Camilla Krakstad, Martha Chekenya

The Runx transcriptional co-activator, CBFβ, is essential for invasion of breast cancer cells

Daniel Mendoza-Villanueva, Wensheng Deng, Cesar Lopez-Camacho, Paul Shore

The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity

Matthew A Bill, James R Fuchs, Chenglong Li, Jennifer Yui, Courtney Bakan, Don M Benson, Eric B Schwartz, Dalia Abdelhamid, Jiayuh Lin, Dale G Hoyt, Stacey L Fossey, Gregory S Young, William E Carson, Pui-Kai Li, Gregory B Lesinski

Personalized therapies in the cancer "omics" era

Alberto Oca？a, Atanasio Pandiella

TRAIL sensitize MDR cells to MDR-related drugs by down-regulation of P-glycoprotein through inhibition of DNA-PKcs/Akt/GSK-3β pathway and activation of caspases

Suk-Bin Seo, Jung-Gu Hur, Mi-Ju Kim, Jae-Won Lee, Hak-Bong Kim, Jae-Ho Bae, Dong-Wan Kim, Chi-Dug Kang, Sun-Hee Kim

Transcriptome analysis of human cancer reveals a functional role of Heme Oxygenase-1 in tumor cell adhesion

Stefanie Tauber, Alexander Jais, Markus Jeitler, Sandra Haider, Julia Husa, Josefine Lindroos, Martin Kn？fler, Matthias Mayerhofer, Hubert Pehamberger, Oswald Wagner, Martin Bilban

Knock down of HIF-1α in glioma cells reduces migration in vitro and invasion in vivo and impairs their ability to form tumor spheres

Olga Méndez, Jiri Zavadil, Mine Esencay, Yevgeniy Lukyanov, Daniel Santovasi, Shu-Chi Wang, Elizabeth W Newcomb, David Zagzag

MicroRNA, hsa-miR-200c, is an independent prognostic factor in pancreatic cancer and its upregulation inhibits pancreatic cancer invasion but increases cell proliferation

Jun Yu, Kenoki Ohuchida, Kazuhiro Mizumoto, Norihiro Sato, Tadashi Kayashima, Hayato Fujita, Kouhei Nakata, Masao Tanaka

TGFBI expression is associated with a better response to chemotherapy in NSCLC

Marta Irigoyen, María J Pajares, Jackeline Agorreta, Mariano Ponz-Sarvisé, Elisabeth Salvo, María D Lozano, Ruben Pío, Ignacio Gil-Bazo, Ana Rouzaut

EGFR isoforms and gene regulation in human endometrial cancer cells

Lina Albitar, Gavin Pickett, Marilee Morgan, Jason A Wilken, Nita J Maihle, Kimberly K Leslie

Elevation of sulfatides in ovarian cancer: An integrated transcriptomic and lipidomic analysis including tissue-imaging mass spectrometry

Ying Liu, Yanfeng Chen, Amin Momin, Rebecca Shaner, Elaine Wang, Nathan J Bowen, Lilya V Matyunina, L Walker, John F McDonald, M Sullards, Alfred H Merrill

Elevated level of anterior gradient-2 in pancreatic juice from patients with pre-malignant pancreatic neoplasia

Ru Chen, Sheng Pan, Xiaobo Duan, Brad H Nelson, Rob A Sahota, Sarah de Rham, Richard A Kozarek, Martin McIntosh, Teresa A Brentnall

Integrin expression profiling identifies integrin alpha5 and beta1 as prognostic factors in early stage non-small cell lung cancer

Anne-Marie C Dingemans, Vivian van den Boogaart, Bettine A Vosse, Robert-Jan van Suylen, Arjan W Griffioen, Victor L Thijssen

The ERα coactivator, HER4/4ICD, regulates progesterone receptor expression in normal and malignant breast epithelium

Jerzy Rokicki, Partha M Das, Jennifer M Giltnane, Olivia Wansbury, David L Rimm, Beatrice A Howard, Frank E Jones

Musashi1 regulates breast tumor cell proliferation and is a prognostic indicator of poor survival

Xiao-Yang Wang, Luiz OF Penalva, Hongyan Yuan, R Ilona Linnoila, Jiachun Lu, Hideyuki Okano, Robert I Glazer

Evaluation of LMP1 of Epstein-Barr virus as a therapeutic target by its inhibition

Adele Hannigan, Joanna B Wilson

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