Journal of Translational Medicine - oalib

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Journal of Translational Medicine

ISSN Print: 1479-5876

ISSN Online:

主页: http://www.translational-medicine.com

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Epstein-Barr virus encoded latent membrane protein 1 regulates mTOR signaling pathway genes which predict poor prognosis of nasopharyngeal carcinoma

Jing Chen, Chun-Fang Hu, Jing-Hui Hou, Qiong Shao, Li-Xu Yan, Xiao-Feng Zhu, Yi-Xin Zeng, Jian-Yong Shao

Cell and gene therapies: moving from research to clinic

David F Stroncek, Raj K Puri

Comparison of T-cell receptor repertoire restriction in blood and tumor tissue of colorectal cancer patients

Sebastian Ochsenreither, Alberto Fusi, Susanne Wojtke, Antonia Busse, Natascha C Nüssler, Eckhard Thiel, Ulrich Keilholz, Dirk Nagorsen

Epidermal growth factor receptor gene copy number in 101 advanced colorectal cancer patients treated with chemotherapy plus cetuximab

Carla Campanella, Marcella Mottolese, Anna Cianciulli, Angela Torsello, Roberta Merola, Isabella Sperduti, Elisa Melucci, Salvatore Conti, Maria Diodoro, Massimo Zeuli, Giancarlo Paoletti, Francesco Cognetti, Carlo Garufi

Endotoxin and CD14 in the progression of biliary atresia

Ming-Huei Chou, Jiin-Haur Chuang, Hock-Liew Eng, Ching-Mei Chen, Chiou-Huey Wang, Chao-Long Chen, Tsun-Mei Lin

Inhibiting adenoid cystic carcinoma cells growth and metastasis by blocking the expression of ADAM 10 using RNA interference

Qin Xu, Xiuming Liu, Wantao Chen, Zhiyuan Zhang

Prevalence of the GJB2 IVS1+1G >A mutation in Chinese hearing loss patients with monoallelic pathogenic mutation in the coding region of GJB2

Yongyi Yuan, Fei Yu, Guojian Wang, Shasha Huang, Ruili Yu, Xin Zhang, Deliang Huang, Dongyi Han, Pu Dai

Thymoglobulin, interferon-γ and interleukin-2 efficiently expand cytokine-induced killer (CIK) cells in clinical-grade cultures

Giuseppina Bonanno, Paola Iudicone, Andrea Mariotti, Annabella Procoli, Annino Pandolfi, Daniela Fioravanti, Maria Corallo, Alessandro Perillo, Giovanni Scambia, Luca Pierelli, Sergio Rutella

Future research and therapeutic applications of human stem cells: general, regulatory, and bioethical aspects

Antonio Liras

Immuno-Oncology biomarkers 2010 and beyond: Perspectives from the iSBTc/SITC biomarker task force

Lisa H Butterfield, Mary L Disis, Samir N Khleif, James M Balwit, Francesco M Marincola

Programmed cell death-1 (PD-1) at the heart of heterologous prime-boost vaccines and regulation of CD8+ T cell immunity

Adrian Bot, Zhiyong Qiu, Raymond Wong, Mihail Obrocea, Kent A Smith

Prevention of hyperglycemia-induced myocardial apoptosis by gene silencing of Toll-like receptor-4

Yuwei Zhang, Tianqing Peng, Huaqing Zhu, Xiufen Zheng, Xusheng Zhang, Nan Jiang, Xiaoshu Cheng, Xiaoyan Lai, Aminah Shunnar, Manpreet Singh, Neil Riordan, Vladimir Bogin, Nanwei Tong, Wei-Ping Min

Morphologic complexity of epithelial architecture for predicting invasive breast cancer survival

Mauro Tambasco, Misha Eliasziw, Anthony M Magliocco

The effect of acyclovir on the tubular secretion of creatinine in vitro

Patrina Gunness, Katarina Aleksa, Gideon Koren

Immunoreactivity of anti-gelsolin antibodies: implications for biomarker validation

Nicole Haverland, Gw？na？l Pottiez, Jayme Wiederin, Pawel Ciborowski

Effects of pegylated G-CSF on immune cell number and function in patients with gynecological malignancies

Giuseppina Bonanno, Annabella Procoli, Andrea Mariotti, Maria Corallo, Alessandro Perillo, Silvio Danese, Raimondo De Cristofaro, Giovanni Scambia, Sergio Rutella

Biotechnology entrepreneurship - where no research has gone before

Michael L Salgaller, Francesco M Marincola

Targeting the inflammation in HCV-associated hepatocellular carcinoma: a role in the prevention and treatment

Giuseppe Castello, Susan Costantini, Stefania Scala

Generalized cerebral atrophy seen on MRI in a naturally exposed animal model for creutzfeldt-jakob disease

Alexia L McKnight, Lawrence A Minkoff, Diane L Sutton, Bruce V Thomsen, Perry L Habecker, Raymond W Sweeney, Gary Smith, Constantin A Dasanu, Thomas E Ichim, Doru T Alexandrescu, Joel M Stutman

DNA polymeraseη protein expression predicts treatment response and survival of metastatic gastric adenocarcinoma patients treated with oxaliplatin-based chemotherapy

Kai-yuan Teng, Miao-zhen Qiu, Zhuang-hua Li, Hui-yan Luo, Zhao-lei Zeng, Rong-zhen Luo, Hui-zhong Zhang, Zhi-qiang Wang, Yu-hong Li, Rui-hua Xu

Epigenetics of human cutaneous melanoma: setting the stage for new therapeutic strategies

Luca Sigalotti, Alessia Covre, Elisabetta Fratta, Giulia Parisi, Francesca Colizzi, Aurora Rizzo, Riccardo Danielli, Hugues JM Nicolay, Sandra Coral, Michele Maio

Strategy Escalation: An emerging paradigm for safe clinical development of T cell gene therapies

Richard Junghans

FRET microscopy autologous tumor lysate processing in mature dendritic cell vaccine therapy

Laura Fiammenghi, Valentina Ancarani, Tilman Rosales, Jay R Knutson, Massimiliano Petrini, Anna Granato, Elena Pancisi, Laura Ridolfi, Ruggero Ridolfi, Angela Riccobon, Paolo Neyroz

Assessing agonistic potential of a candidate therapeutic anti-IL21R antibody

Yongjing Guo, Andrew A Hill, Renee C Ramsey, Frederick W Immermann, Christopher Corcoran, Deborah Young, Edward R LaVallie, Mark Ryan, Theresa Bechard, Richard Pfeifer, Garvin Warner, Marcia Bologna, Laird Bloom, Margot O'Toole

Decreased level of recent thymic emigrants in CD4+ and CD8+T cells from CML patients

Yangqiu Li, Suxia Geng, Qingsong Yin, Shaohua Chen, Lijian Yang, Xiuli Wu, Bo Li, Xin Du, Christian A Schmidt, Grzegorz K Przybylski

Proton dynamics in cancer

Veronica Huber, Angelo De Milito, Salvador Harguindey, Stephan J Reshkin, Miriam L Wahl, Cyril Rauch, Antonio Chiesi, Jacques Pouysségur, Robert A Gatenby, Licia Rivoltini, Stefano Fais

Prognostic impact of clinical course-specific mRNA expression profiles in the serum of perioperative patients with esophageal cancer in the ICU: a case control study

Shunsaku Takahashi, Norimasa Miura, Tomomi Harada, ZhongZhi Wang, Xinhui Wang, Hideyuki Tsubokura, Yoshiaki Oshima, Junichi Hasegawa, Yoshimi Inagaki, Goshi Shiota

One Step Nucleic Acid Amplification (OSNA) - a new method for lymph node staging in colorectal carcinomas

Roland S Croner, Vera Schellerer, Helene Demund, Claus Schildberg, Thomas Papadopulos, Elisabeth Naschberger, Michael Stürzl, Klaus E Matzel, Werner Hohenberger, Anne Schlabrakowski

Treatment combining RU486 and Ad5IL-12 vector attenuates the growth of experimentally formed prostate tumors and induces changes in the sentinel lymph nodes of mice

Claudia Gabaglia, Alexandra DeLaney, Jennifer Gee, Ramesh Halder, Frank L Graham, Jack Gauldie, Eli E Sercarz, Todd A Braciak

Early combined treatment with sildenafil and adipose-derived mesenchymal stem cells preserves heart function in rat dilated cardiomyopathy

Yu-Chun Lin, Steve Leu, Cheuk-Kwan Sun, Chia-Hung Yen, Ying-Hsien Kao, Li-Teh Chang, Tzu-Hsien Tsai, Sarah Chua, Morgan Fu, Sheung-Fat Ko, Chiung-Jen Wu, Fan-Yen Lee, Hon-Kan Yip

Prognostic significance of Oct4 and Sox2 expression in hypopharyngeal squamous cell carcinoma

Nan Ge, Huan-Xin Lin, Xiang-Sheng Xiao, Ling Guo, Hui-Min Xu, Xin Wang, Ting Jin, Xiu-Yu Cai, Yi Liang, Wei-Han Hu, Tiebang Kang

Development of targeted therapy for bladder cancer mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences

Doron Amit, Abraham Hochberg

Human cord blood progenitors with high aldehyde dehydrogenase activity improve vascular density in a model of acute myocardial infarction

Claus S Sondergaard, David A Hess, Dustin J Maxwell, Carla Weinheimer, Ivana Rosová, Michael H Creer, David Piwnica-Worms, Attila Kovacs, Lene Pedersen, Jan A Nolta

Bridging the Divide between Science and Journalism

Laura Van Eperen, Francesco M Marincola, Jennifer Strohm

Papillomavirus pseudovirions packaged with the L2 gene induce cross-neutralizing antibodies

Nicolas Combelas, Emilie Saussereau, Maxime JJ Fleury, Tatiana Ribeiro, Julien Gaitan, Diego F Duarte-Forero, Pierre Coursaget, Antoine Touzé

Abdominal irradiation modulates 5-Fluorouracil pharmacokinetics

Chen-Hsi Hsieh, Yen-Ju Hsieh, Chia-Yuan Liu, Hung-Chi Tai, Yu-Chuen Huang, Pei-Wei Shueng, Le-Jung Wu, Li-Ying Wang, Tung-Hu Tsai, Yu-Jen Chen

"Hypoxia-induced down-regulation of microRNA-449a/b impairs control over targeted SERPINE1 (PAI-1) mRNA - a mechanism involved in SERPINE1 (PAI-1) overexpression"

Michaela Muth, Katharina Theophile, Kais Hussein, Christoph Jacobi, Hans Kreipe, Oliver Bock

Nutraceutical augmentation of circulating endothelial progenitor cells and hematopoietic stem cells in human subjects

Nina A Mikirova, James A Jackson, Ron Hunninghake, Julian Kenyon, Kyle WH Chan, Cathy A Swindlehurst, Boris Minev, Amit N Patel, Michael P Murphy, Leonard Smith, Famela Ramos, Thomas E Ichim, Neil H Riordan

Oxidative stress in NSC-741909-induced apoptosis of cancer cells

Xiaoli Wei, Wei Guo, Shuhong Wu, Li Wang, Peng Huang, Jinsong Liu, Bingliang Fang

Fowlpox virus recombinants expressing HPV-16 E6 and E7 oncogenes for the therapy of cervical carcinoma elicit humoral and cell-mediated responses in rabbits

Antonia Radaelli, Eleana Pozzi, Sole Pacchioni, Carlo Zanotto, Carlo Morghen

CCL20/CCR6 expression profile in pancreatic cancer

Claudia Rubie, Vilma Frick, Pirus Ghadjar, Mathias Wagner, Henner Grimm, Benjamin Vicinus, Christoph Justinger, Stefan Graeber, Martin K Schilling

The effect of an autologous cellular gel-matrix integrated implant system on wound healing

Caroline R Weinstein-Oppenheimer, Alexis R Aceituno, Donald I Brown, Cristian Acevedo, Ricardo Ceriani, Miguel A Fuentes, Fernando Albornoz, Carlos F Henríquez-Roldán, Patricio Morales, Claudio Maclean, Sergio M Tapia, Manuel E Young

Overexpression of microRNA-206 in the skeletal muscle from myotonic dystrophy type 1 patients

Stefano Gambardella, Fabrizio Rinaldi, Saverio M Lepore, Antonella Viola, Emanuele Loro, Corrado Angelini, Lodovica Vergani, Giuseppe Novelli, Annalisa Botta

Development and application of a biomarker assay for determining the pharmacodynamic activity of an antagonist candidate biotherapeutic antibody to IL21R in whole blood

Maya Arai, Sadhana Jain, Amy A Weaver, Andrew A Hill, Yongjing Guo, Andrea G Bree, Michael F Smith, Scott W Allen, Edward R LaVallie, Deborah Young, Laird Bloom, Karissa Adkins, Margot O'Toole

Regulatory T cell frequency in patients with melanoma with different disease stage and course, and modulating effects of high-dose interferon-α 2b treatment

Paolo A Ascierto, Maria Napolitano, Egidio Celentano, Ester Simeone, Giusy Gentilcore, Antonio Daponte, Mariaelena Capone, Corrado Caracò, Rosa Calemma, Gerardo Beneduce, Margherita Cerrone, Vincenzo De Rosa, Giuseppe Palmieri, Giuseppe Castello, John M Kirkwood, Francesco M Marincola, Nicola Mozzillo

Three-day dendritic cells for vaccine development: Antigen uptake, processing and presentation

Maja Bürdek, Stefani Spranger, Susanne Wilde, Bernhard Frankenberger, Dolores J Schendel, Christiane Geiger

Evaluation of six CTLA-4 polymorphisms in high-risk melanoma patients receiving adjuvant interferon therapy in the He13A/98 multicenter trial

Helen Gogas, Urania Dafni, Henry Koon, Maria Spyropoulou-Vlachou, Yannis Metaxas, Elizabeth Buchbinder, Eirini Pectasides, Dimosthenis Tsoutsos, Aristidis Polyzos, Alexandros Stratigos, Christos Markopoulos, Petros Panagiotou, George Fountzilas, Ourania Castana, Pantelis Skarlos, Michael B Atkins, John M Kirkwood

Exhaustive expansion: A novel technique for analyzing complex data generated by higher-order polychromatic flow cytometry experiments

Janet C Siebert, Lian Wang, Daniel P Haley, Ann Romer, Bo Zheng, Wes Munsil, Kenton W Gregory, Edwin B Walker

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