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PLOS Genetics

ISSN Print: 1553-7390

ISSN Online:

主页: http://www.plosgenetics.org/article/browse/volume

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X Chromosome: Expression and Escape

John Parsch

A Constant Light-Genetic Screen Identifies KISMET as a Regulator of Circadian Photoresponses

Rapha？lle Dubruille,Alejandro Murad,Michael Rosbash,Patrick Emery

Progressive GAA·TTC Repeat Expansion in Human Cell Lines

Scott Ditch,Mimi C. Sammarco,Ayan Banerjee,Ed Grabczyk

Adaptive Evolution in Zinc Finger Transcription Factors

Ryan O. Emerson,James H. Thomas

Fission Yeast Tel1ATM and Rad3ATR Promote Telomere Protection and Telomerase Recruitment

Bettina A. Moser,Lakxmi Subramanian,Lyne Khair,Ya-Ting Chang,Toru M. Nakamura

Identification of a Cardiac Disease Modifier Gene Using Forward Genetics in the Mouse

William T. Pu

Inositol 1,4,5-Trisphosphate Signalling Regulates the Avoidance Response to Nose Touch in Caenorhabditis elegans

Denise S. Walker ,Rafael P. Vázquez-Manrique,Nicholas J. D. Gower,Elizabeth Gregory,William R. Schafer,Howard A. Baylis

Nucleolar Proteins Suppress Caenorhabditis elegans Innate Immunity by Inhibiting p53/CEP-1

Laura E. Fuhrman,Ajay Kumar Goel,Jason Smith,Kevin V. Shianna,Alejandro Aballay

Molecular Tooth Decay

Rob DeSalle

GASZ Is Essential for Male Meiosis and Suppression of Retrotransposon Expression in the Male Germline

Lang Ma equal contributor,Gregory M. Buchold equal contributor,Michael P. Greenbaum,Angshumoy Roy,Kathleen H. Burns,Huifeng Zhu,Derek Y. Han,R. Alan Harris,Cristian Coarfa,Preethi H. Gunaratne ？,Wei Yan ？,Martin M. Matzuk

Wonderful Life: An Interview with Herb Boyer

Jane Gitschier

Nuclear Calcium Signaling Controls Expression of a Large Gene Pool: Identification of a Gene Program for Acquired Neuroprotection Induced by Synaptic Activity

Sheng-Jia Zhang,Ming Zou,Li Lu,David Lau,Désirée A. W. Ditzel,Celine Delucinge-Vivier,Yoshinori Aso,Patrick Descombes,Hilmar Bading

SCA8 CAG/CTG Expansions, a Tale of Two TOXICities: A Unique or Common Case?

Karine Merienne,Yvon Trottier

Alternative Mechanisms for Tn5 Transposition

Asad Ahmed

PCH'ing Together an Understanding of Crossover Control

Drew Thacker,Scott Keeney

On Quality Control Measures in Genome-Wide Association Studies: A Test to Assess the Genotyping Quality of Individual Probands in Family-Based Association Studies and an Application to the HapMap Data

David W. Fardo,Iuliana Ionita-Laza,Christoph Lange

Notch and Prospero Repress Proliferation following Cyclin E Overexpression in the Drosophila Bristle Lineage

Fran？oise Simon,Pierre Fichelson,Michel Gho,Agnès Audibert

Scientists←Editors←Scientists: The Past, Present, and Future of PLoS Genetics

Gregory S. Barsh ,Gregory P. Copenhaver

Tnni3k Modifies Disease Progression in Murine Models of Cardiomyopathy

Ferrin C. Wheeler,Hao Tang,Odessa A. Marks,Tracy N. Hadnott,Pei-Lun Chu,Lan Mao,Howard A. Rockman,Douglas A. Marchuk

Broad-Scale Recombination Patterns Underlying Proper Disjunction in Humans

Adi Fledel-Alon,Daniel J. Wilson,Karl Broman,Xiaoquan Wen,Carole Ober,Graham Coop ？,Molly Przeworski ？

The Bantam microRNA Is Associated with Drosophila Fragile X Mental Retardation Protein and Regulates the Fate of Germline Stem Cells

Yingyue Yang equal contributor,Shunliang Xu equal contributor,Laixin Xia,Jun Wang,Shengmei Wen,Peng Jin ,Dahua Chen

Life, Death, Differentiation, and the Multicellularity of Bacteria

Susan M. Rosenberg

A Human Protein Interaction Network Shows Conservation of Aging Processes between Human and Invertebrate Species

Russell Bell equal contributor,Alan Hubbard equal contributor,Rakesh Chettier equal contributor,Di Chen,John P. Miller,Pankaj Kapahi,Mark Tarnopolsky,Sudhir Sahasrabuhde,Simon Melov,Robert E. Hughes

Uncoupling Time and Space in the Collinear Regulation of Hox Genes

Patrick Tschopp,Basile Tarchini,Fran？ois Spitz,Jozsef Zakany,Denis Duboule

Neocentromeres Come of Age

Owen J. Marshall,K. H. Andy Choo

Conservation and Convergence of Colour Genetics: MC1R Mutations in brown Cavefish

Nicholas I. Mundy

Identifying Relationships among Genomic Disease Regions: Predicting Genes at Pathogenic SNP Associations and Rare Deletions

Soumya Raychaudhuri ,Robert M. Plenge,Elizabeth J. Rossin,Aylwin C. Y. Ng,International Schizophrenia Consortium,Shaun M. Purcell,Pamela Sklar,Edward M. Scolnick,Ramnik J. Xavier,David Altshuler,Mark J. Daly

The Mysteries of Chromosome Evolution in Gibbons: Methylation Is a Prime Suspect

Judith D. Brown,Rachel J. O'Neill

The Drosophila foraging Gene Mediates Adult Plasticity and Gene–Environment Interactions in Behaviour, Metabolites, and Gene Expression in Response to Food Deprivation

Clement F. Kent,Tim Daskalchuk,Lisa Cook,Marla B. Sokolowski ,Ralph J. Greenspan

You Say You Want a Revolution: An Interview with Pat Brown

Jane Gitschier

Two Chromatin Remodeling Activities Cooperate during Activation of Hormone Responsive Promoters

Guillermo Pablo Vicent equal contributor,Roser Zaurin equal contributor,A. Silvina Nacht,Ang Li,Jofre Font-Mateu,Francois Le Dily,Michiel Vermeulen,Matthias Mann,Miguel Beato

Prediction and Interaction in Complex Disease Genetics: Experience in Type 1 Diabetes

David G. Clayton

Clustering of Codons with Rare Cognate tRNAs in Human Genes Suggests an Extra Level of Expression Regulation

Joanna L. Parmley ,Martijn A. Huynen

A Computational Screen for Regulators of Oxidative Phosphorylation Implicates SLIRP in Mitochondrial RNA Homeostasis

Joshua M. Baughman,Roland Nilsson,Vishal M. Gohil,Daniel H. Arlow,Zareen Gauhar,Vamsi K. Mootha

Forests of the Night: Refugia of Genetic Diversity in Wild Tigers

Oliver A. Ryder

The pch2Δ Mutation in Baker's Yeast Alters Meiotic Crossover Levels and Confers a Defect in Crossover Interference

Sarah Zanders,Eric Alani

Evolution of a Novel Appendage Ground Plan in Water Striders Is Driven by Changes in the Hox Gene Ultrabithorax

Abderrahman Khila,Ehab Abouheif,Locke Rowe

CA8 Mutations Cause a Novel Syndrome Characterized by Ataxia and Mild Mental Retardation with Predisposition to Quadrupedal Gait

Seval Türkmen equal contributor,Gao Guo equal contributor,Masoud Garshasbi,Katrin Hoffmann,Amjad J. Alshalah,Claudia Mischung,Andreas Kuss,Nicholas Humphrey,Stefan Mundlos,Peter N. Robinson

The Yeast Pif1 Helicase Prevents Genomic Instability Caused by G-Quadruplex-Forming CEB1 Sequences In Vivo

Cyril Ribeyre equal contributor,Judith Lopes equal contributor,Jean-Baptiste Boulé,Aurèle Piazza,Aurore Guédin,Virginia A. Zakian,Jean-Louis Mergny,Alain Nicolas

Complex Adaptations Can Drive the Evolution of the Capacitor [PSI+], Even with Realistic Rates of Yeast Sex

Cortland K. Griswold,Joanna Masel

Systematic Identification of Balanced Transposition Polymorphisms in Saccharomyces cerevisiae

Dina A. Faddah,Eric W. Ganko,Caroline McCoach,Joseph K. Pickrell,Sean E. Hanlon,Frederick G. Mann,Joanna O. Mieczkowska,Corbin D. Jones,Jason D. Lieb ,Todd J. Vision

Enhanced Disease Susceptibility 1 and Salicylic Acid Act Redundantly to Regulate Resistance Gene-Mediated Signaling

Srivathsa C. Venugopal,Rae-Dong Jeong,Mihir K. Mandal,Shifeng Zhu,A. C. Chandra-Shekara,Ye Xia,Matthew Hersh,Arnold J. Stromberg,DuRoy Navarre,Aardra Kachroo,Pradeep Kachroo

Defects in tRNA Modification Associated with Neurological and Developmental Dysfunctions in Caenorhabditis elegans Elongator Mutants

Changchun Chen,Simon Tuck ,Anders S. Bystr？m

Change of Gene Structure and Function by Non-Homologous End-Joining, Homologous Recombination, and Transposition of DNA

Wolfgang Goettel,Joachim Messing

Cytoplasmic Streaming in Neurospora: Disperse the Plug To Increase the Flow?

Michael Plamann

Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution

Cecilia M. Lindgren equal contributor,Iris M. Heid equal contributor,Joshua C. Randall equal contributor,Claudia Lamina equal contributor,Valgerdur Steinthorsdottir equal contributor,Lu Qi,Elizabeth K. Speliotes,Gudmar Thorleifsson,Cristen J. Willer,Blanca M. Herrera,Anne U. Jackson,Noha Lim,Paul Scheet,Nicole Soranzo,Najaf Amin,Yurii S. Aulchenko,John C. Chambers,Alexander Drong,Jian'an Luan,Helen N. Lyon,Fernando Rivadeneira,Serena Sanna,Nicholas J. Timpson,M. Carola Zillikens,Jing Hua Zhao,Peter Almgren,Stefania Bandinelli,Amanda J. Bennett,Richard N. Bergman,Lori L. Bonnycastle,Suzannah J. Bumpstead,Stephen J. Chanock,Lynn Cherkas,Peter Chines,Lachlan Coin,Cyrus Cooper,Gabriel Crawford,Angela Doering,Anna Dominiczak,Alex S. F. Doney,Shah Ebrahim,Paul Elliott,Michael R. Erdos,Karol Estrada,Luigi Ferrucci,Guido Fischer,Nita G. Forouhi,Christian Gieger,Harald Grallert,Christopher J. Groves,Scott Grundy,Candace Guiducci,David Hadley,Anders Hamsten,Aki S. Havulinna,Albert Hofman,Rolf Holle,John W. Holloway,Thomas Illig,Bo Isomaa,Leonie C. Jacobs,Karen Jameson,Pekka Jousilahti,Fredrik Karpe,Johanna Kuusisto,Jaana Laitinen,G. Mark Lathrop,Debbie A. Lawlor,Massimo Mangino,Wendy L. McArdle,Thomas Meitinger,Mario A. Morken,Andrew P. Morris,Patricia Munroe,Narisu Narisu,Anna Nordstr？m,Peter Nordstr？m,Ben A. Oostra,Colin N. A. Palmer,Felicity Payne,John F. Peden,Inga Prokopenko,Frida Renstr？m,Aimo Ruokonen,Veikko Salomaa,Manjinder S. Sandhu,Laura J. Scott,Angelo Scuteri

Forging Links between Human Mental Retardation–Associated CNVs and Mouse Gene Knockout Models

Caleb Webber,Jayne Y. Hehir-Kwa,Duc-Quang Nguyen,Bert B. A. de Vries,Joris A. Veltman ,Chris P. Ponting

Reconstructing the History of Yeast Genomes

David Sankoff

Additions, Losses, and Rearrangements on the Evolutionary Route from a Reconstructed Ancestor to the Modern Saccharomyces cerevisiae Genome

Jonathan L. Gordon,Kevin P. Byrne,Kenneth H. Wolfe

XY and ZW: Is Meiotic Sex Chromosome Inactivation the Rule in Evolution?

Satoshi H. Namekawa,Jeannie T. Lee

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