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PLOS ONE

ISSN Print: 1932-6203

ISSN Online:

主页: http://www.plosone.org/

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Refractory Period Modulates the Spatiotemporal Evolution of Cortical Spreading Depression: A Computational Study

Bing Li, Shangbin Chen, Pengcheng Li, Qingming Luo, Hui Gong

Two Different Conformations in Hepatitis C Virus p7 Protein Account for Proton Transport and Dye Release

Siok Wan Gan, Wahyu Surya, Ardcharaporn Vararattanavech, Jaume Torres

Flavoprotein Autofluorescence Imaging of Visual System Activity in Zebra Finches and Mice

Neethu Michael, Hans-Joachim Bischof, Siegrid L？wel

Full-Genome Analysis of a Canine Pneumovirus Causing Acute Respiratory Disease in Dogs, Italy

Nicola Decaro, Pierfrancesco Pinto, Viviana Mari, Gabriella Elia, Vittorio Larocca, Michele Camero, Valentina Terio, Michele Losurdo, Vito Martella, Canio Buonavoglia

Protective Immunity against Lethal F. tularensis holarctica LVS Provided by Vaccination with Selected Novel CD8+ T Cell Epitopes

Shahar Rotem, Ofer Cohen, Erez Bar-Haim, Liat Bar-On, Sharon Ehrlich, Avigdor Shafferman

Combined Therapy of Iron Chelator and Antioxidant Completely Restores Brain Dysfunction Induced by Iron Toxicity

Jirapas Sripetchwandee, Noppamas Pipatpiboon, Nipon Chattipakorn, Siriporn Chattipakorn

Inter- and Intra-Patient Heterogeneity of Response and Progression to Targeted Therapy in Metastatic Melanoma

Alexander M. Menzies, Lauren E. Haydu, Matteo S. Carlino, Mary W. F. Azer, Peter J. A. Carr, Richard F. Kefford, Georgina V. Long

HCV Genomic RNA Activates the NLRP3 Inflammasome in Human Myeloid Cells

Wei Chen, Yongfen Xu, Hua Li, Wanyin Tao, Yu Xiang, Bing Huang, Junqi Niu, Jin Zhong, Guangxun Meng

miR-223 Is a Coordinator of Breast Cancer Progression as Revealed by Bioinformatics Predictions

Eva Maria Pinatel, Francesca Orso, Elisa Penna, Daniela Cimino, Angela Rita Elia, Paola Circosta, Patrizia Dentelli, Maria Felice Brizzi, Paolo Provero, Daniela Taverna

Basal Keratinocytes Contribute to All Strata of the Adult Zebrafish Epidermis

Raymond T. H. Lee, P. V. Asharani, Thomas J. Carney

Defining the Ligand Specificity of the Deleted in Colorectal Cancer (DCC) Receptor

Patrick C. G. Haddick, Irene Tom, Elizabeth Luis, Gabriel Qui？ones, Bernd J. Wranik, Sree R. Ramani, Jean-Philippe Stephan, Marc Tessier-Lavigne, Lino C. Gonzalez

Association between HIV/AIDS and Multi-Drug Resistance Tuberculosis: A Systematic Review and Meta-Analysis

Yonatan Moges Mesfin, Damen Hailemariam, Sibhatu Biadglign, Kelemu Tilahun Kibret

De Novo Transcriptome Assembly from Fat Body and Flight Muscles Transcripts to Identify Morph-Specific Gene Expression Profiles in Gryllus firmus

Neetha Nanoth Vellichirammal, Anthony J. Zera, Rudolf J. Schilder, Cody Wehrkamp, Jean-Jack M. Riethoven, Jennifer A. Brisson

ZODET: Software for the Identification, Analysis and Visualisation of Outlier Genes in Microarray Expression Data

Daniel L. Roden, Gavin W. Sewell, Anna Lobley, Adam P. Levine, Andrew M. Smith, Anthony W. Segal

Maturity Ogives for South Pacific Albacore Tuna (Thunnus alalunga) That Account for Spatial and Seasonal Variation in the Distributions of Mature and Immature Fish

Jessica H. Farley, Simon D. Hoyle, J. Paige Eveson, Ashley J. Williams, Campbell R. Davies, Simon J. Nicol

Endogenous CNS Expression of Neurotensin and Neurotensin Receptors Is Altered during the Postpartum Period in Outbred Mice

Terri M. Driessen, Changjiu Zhao, Anna Whittlinger, Horecia Williams, Stephen C. Gammie

NPPB and ACAN, Two Novel SHOX2 Transcription Targets Implicated in Skeletal Development

Miriam Aza-Carmona, Veronica Barca-Tierno, Alfonso Hisado-Oliva, Alberta Belinchón, Darya Gorbenko-del Blanco, Jose Ignacio Rodriguez, Sara Benito-Sanz, Angel Campos-Barros, Karen E. Heath

Strong Relationship between Oral Dose and Tenofovir Hair Levels in a Randomized Trial: Hair as a Potential Adherence Measure for Pre-Exposure Prophylaxis (PrEP)

Albert Y. Liu, Qiyun Yang, Yong Huang, Peter Bacchetti, Peter L. Anderson, Chengshi Jin, Kathy Goggin, Kristefer Stojanovski, Robert Grant, Susan P. Buchbinder, Ruth M. Greenblatt, Monica Gandhi

Antibody Responses to a Novel Plasmodium falciparum Merozoite Surface Protein Vaccine Correlate with Protection against Experimental Malaria Infection in Aotus Monkeys

David R. Cavanagh, Clemens H. M. Kocken, John H. White, Graeme J. M. Cowan, Kay Samuel, Martin A. Dubbeld, Annemarie Voorberg-van der Wel, Alan W. Thomas, Jana S. McBride, David E. Arnot

Impact of Universal Health Insurance Coverage on Hypertension Management: A Cross-National Study in the United States and England

Andrew R. H. Dalton, Eszter P. Vamos, Matthew J. Harris, Gopalakrishnan Netuveli, Robert M. Wachter, Azeem Majeed, Christopher Millett

Identifying Optimal Models to Represent Biochemical Systems

Mochamad Apri, Maarten de Gee, Simon van Mourik, Jaap Molenaar

Culicoides Midge Bites Modulate the Host Response and Impact on Bluetongue Virus Infection in Sheep

Nonito Pages, Emmanuel Bréard, Céline Urien, Sandra Talavera, Cyril Viarouge, Cristina Lorca-Oro, Luc Jouneau, Bernard Charley, Stéphan Zientara, Albert Bensaid, David Solanes, Joan Pujols, Isabelle Schwartz-Cornil

An Inflammation Based Score Can Optimize the Selection of Patients with Advanced Cancer Considered for Early Phase Clinical Trials

David J. Pinato, Chara Stavraka, Michael J. Flynn, Martin D. Forster, Séan M. O'Cathail, Michael J. Seckl, Rebecca S. Kristeleit, David Olmos, Samantha J. Turnbull, Sarah P. Blagden

Prevention of UVA-Induced Oxidative Damage in Human Dermal Fibroblasts by New UV Filters, Assessed Using a Novel In Vitro Experimental System

Francesca Brugè, Luca Tiano, Paola Astolfi, Monica Emanuelli, Elisabetta Damiani

Gas6 Stimulates Angiogenesis of Human Retinal Endothelial Cells and of Zebrafish Embryos via ERK1/2 Signaling

Young Sook Kim, Seung-Hyun Jung, Dong Ho Jung, So-Jin Choi, Yu-Ri Lee, Jin Sook Kim

Combining Organophosphate Treated Wall Linings and Long-lasting Insecticidal Nets for Improved Control of Pyrethroid Resistant Anopheles gambiae

Corine Ngufor, Emile Tchicaya, Benjamin Koudou, Sagnon N'Fale, Roch Dabire, Paul Johnson, Hilary Ranson, Mark Rowland

A Staging Scheme for the Development of the Scuttle Fly Megaselia abdita

Karl R. Wotton, Eva Jiménez-Guri, Belén García Matheu, Johannes Jaeger

A Staging Scheme for the Development of the Moth Midge Clogmia albipunctata

Eva Jiménez-Guri, Karl R. Wotton, Brenda Gavilán, Johannes Jaeger

A Cost Effectiveness Analysis of Salt Reduction Policies to Reduce Coronary Heart Disease in Four Eastern Mediterranean Countries

Helen Mason, Azza Shoaibi, Rula Ghandour, Martin O'Flaherty, Simon Capewell, Rana Khatib, Samer Jabr, Belgin Unal, Kaan S？zmen, Chokri Arfa, Wafa Aissi, Habiba Ben Romdhane, Fouad Fouad, Radwan Al-Ali, Abdullatif Husseini, the MedCHAMPS project team

Salivary Inflammatory Mediator Profiling and Correlation to Clinical Disease Markers in Asthma

Frédéric F. Little, Diana M. Delgado, Philip J. Wexler, Frank G. Oppenheim, Patricia Mitchell, James A. Feldman, David R. Walt, Roger D. Peng, Elizabeth C. Matsui

Probing the Subcellular Localization of Hopanoid Lipids in Bacteria Using NanoSIMS

David M. Doughty, Michael Dieterle, Alex L. Sessions, Woodward W. Fischer, Dianne K. Newman

Polymorphism of Leukocyte and Erythrocyte Antigens in Chronic Kidney Disease Patients in Southern Brazil

Roger Haruki Yamakawa, Patricia Keiko Saito, Waldir Veríssimo da Silva Junior, Luiz Carlos de Mattos, Sueli Donizete Borelli

PTK 7 Is a Transforming Gene and Prognostic Marker for Breast Cancer and Nodal Metastasis Involvement

Silvia G？rtner, Angela Gunesch, Tatiana Knyazeva, Petra Wolf, Bernhard H？gel, Wolfgang Eiermann, Axel Ullrich, Pjotr Knyazev, Beyhan Ataseven

Visualizing Cell State Transition Using Raman Spectroscopy

Taro Ichimura, Liang-da Chiu, Katsumasa Fujita, Satoshi Kawata, Tomonobu M. Watanabe, Toshio Yanagida, Hideaki Fujita

Fluctuating Selection Models and Mcdonald-Kreitman Type Analyses

Toni I. Gossmann, David Waxman, Adam Eyre-Walker

A Mismatch between the Perceived Fighting Signal and Fighting Ability Reveals Survival and Physiological Costs for Bearers

Isaac González-Santoyo, Daniel M. González-Tokman, Roberto E. Munguía-Steyer, Alex Córdoba-Aguilar

In Vivo Mitochondrial Function in HIV-Infected Persons Treated with Contemporary Anti-Retroviral Therapy: A Magnetic Resonance Spectroscopy Study

Brendan A. I. Payne, Kieren G. Hollingsworth, Joanne Baxter, Edmund Wilkins, Vincent Lee, D. Ashley Price, Michael Trenell, Patrick F. Chinnery

Loss of Hippocampal Neurons after Kainate Treatment Correlates with Behavioral Deficits

Gisela H. Maia, José L. Quesado, Joana I. Soares, Joana M. do Carmo, Pedro A. Andrade, José P. Andrade, Nikolai V. Lukoyanov

Inhibition of HIF prolyl-4-hydroxylases by FG-4497 Reduces Brain Tissue Injury and Edema Formation during Ischemic Stroke

Stefan Reischl, Lexiao Li, Gail Walkinshaw, Lee A. Flippin, Hugo H. Marti, Reiner Kunze

Regional Gray Matter Volume Is Associated with Empathizing and Systemizing in Young Adults

Hikaru Takeuchi, Yasuyuki Taki, Yuko Sassa, Hiroshi Hashizume, Atsushi Sekiguchi, Ai Fukushima, Ryuta Kawashima

Assessment of Whole Genome Amplification for Sequence Capture and Massively Parallel Sequencing

Johanna Hasmats, Henrik Gréen, Cedric Orear, Pierre Validire, Mikael Huss, Max K？ller, Joakim Lundeberg

Growth Promotion-Related miRNAs in Oncidium Orchid Roots Colonized by the Endophytic Fungus Piriformospora indica

Wei Ye, Chin-Hui Shen, Yuling Lin, Peng-Jen Chen, Xuming Xu, Ralf Oelmüller, Kai-Wun Yeh, Zhongxiong Lai

Identification and Expression Analysis of Diapause Hormone and Pheromone Biosynthesis Activating Neuropeptide (DH-PBAN) in the Legume Pod Borer, Maruca vitrata Fabricius

Jian-Cheng Chang, Srinivasan Ramasamy

mRNA Levels of Related Abcb Genes Change Opposite to Each Other upon Histone Deacetylase Inhibition in Drug-Resistant Rat Hepatoma Cells

ádám Sike, Enik？ Nagy, Balázs Vedelek, Dávid Pusztai, Péter Szerémy, Anikó Venetianer, Imre M. Boros

Phenylalanine Metabolism Regulates Reproduction and Parasite Melanization in the Malaria Mosquito

Silke Fuchs, Volker Behrends, Jacob G. Bundy, Andrea Crisanti, Tony Nolan

DUSP1 Is a Novel Target for Enhancing Pancreatic Cancer Cell Sensitivity to Gemcitabine

Fang Liu, A. Jesse Gore, Julie L. Wilson, Murray Korc

Ovarian Cancer Spheroid Cells with Stem Cell-Like Properties Contribute to Tumor Generation, Metastasis and Chemotherapy Resistance through Hypoxia-Resistant Metabolism

Jianqun Liao, Feng Qian, Nana Tchabo, Paulette Mhawech-Fauceglia, Amy Beck, Zikun Qian, Xinhui Wang, Wendy J. Huss, Shashikant B. Lele, Carl D. Morrison, Kunle Odunsi

Telomerase Inhibitor Imetelstat (GRN163L) Limits the Lifespan of Human Pancreatic Cancer Cells

Katrina M. Burchett, Ying Yan, Michel M. Ouellette

Development of a Preclinical Orthotopic Xenograft Model of Ewing Sarcoma and Other Human Malignant Bone Disease Using Advanced In Vivo Imaging

Britta Vormoor, Henrike K. Knizia, Michael A. Batey, Gilberto S. Almeida, Ian Wilson, Petra Dildey, Abhishek Sharma, Helen Blair, I. Geoff Hide, Olaf Heidenreich, Josef Vormoor, Ross J. Maxwell, Chris M. Bacon

Membrane Labeling of Coral Gastrodermal Cells by Biotinylation: The Proteomic Identification of Surface Proteins Involving Cnidaria-Dinoflagellate Endosymbiosis

Hsing-Hui Li, Zi-Yu Huang, Shih-Png Ye, Chi-Yu Lu, Pai-Chiao Cheng, Shu-Hwa Chen, Chii-Shiarng Chen

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