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OALib Journal期刊
ISSN: 2333-9721
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主页: https://pubs.acs.org/journal/acbcct

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Peptide-Membrane Interactions Affect the Inhibitory Potency and Selectivity of Spider Toxins ProTx-II and GpTx-1

A Cancer-Selective Zinc Ionophore Inspired by the Natural Product Naamidine A

Improving Selectivity, Proteolytic Stability, and Antitumor Activity of Hymenochirin-1B: A Novel Glycosylated Staple Strategy

Engineering Atypical Tetracycline Formation in Amycolatopsis sulphurea for the Production of Modified Chelocardin Antibiotics

Small Molecule SOS1 Agonists Modulate MAPK and PI3K Signaling via Independent Cellular Responses

Engineering NaV1.7 Inhibitory JzTx-V Peptides with a Potency and Basicity Profile Suitable for Antibody Conjugation To Enhance Pharmacokinetics

Deconvoluting Stress-Responsive Proteostasis Signaling Pathways for Pharmacologic Activation Using Targeted RNA Sequencing

MAGI: A Method for Metabolite Annotation and Gene Integration

Hyperpolarized [6-13C,15N3]-Arginine as a Probe for in Vivo Arginase Activity

Development of a Suicide Inhibition-Based Protein Labeling Strategy for Nicotinamide N-Methyltransferase

Engineering of Chimeric Polyketide Synthases Using SYNZIP Docking Domains

Multifunctionalization of Cells with a Self-Assembling Molecule to Enhance Cell Engraftment

Cu-ATCUN Derivatives of Sub5 Exhibit Enhanced Antimicrobial Activity via Multiple Modes of Action

Abnormal Cannabidiol Modulates Vitamin A Metabolism by Acting as a Competitive Inhibitor of CRBP1

Fimsbactin and Acinetobactin Compete for the Periplasmic Siderophore Binding Protein BauB in Pathogenic Acinetobacter baumannii

Bioactivity-HiTES Unveils Cryptic Antibiotics Encoded in Actinomycete Bacteria

A Chemical Inhibitor of Cell Growth Reduces Cell Size in Bacillus subtilis

Unique Biosynthetic Pathway in Bloom-Forming Cyanobacterial Genus Microcystis Jointly Assembles Cytotoxic Aeruginoguanidines and Microguanidines

Tryptophan Metabolism in Caenorhabditis elegans Links Aggregation Behavior to Nutritional Status

Developing Workflow for Simultaneous Analyses of Phosphopeptides and Glycopeptides

New Molecular Scaffolds for Fluorescent Voltage Indicators

Molecular Basis of Bacillus subtilis ATCC 6633 Self-Resistance to the Phosphono-oligopeptide Antibiotic Rhizocticin

Colloidal Drug Aggregate Stability in High Serum Conditions and Pharmacokinetic Consequence

Biosynthetic Basis for Structural Diversity of Aminophenylpyrrole-Derived Alkaloids

Esterase-Triggered Self-Immolative Thiocarbamates Provide Insights into COS Cytotoxicity

Efficient Intracellular Delivery of CRISPR-Cas Ribonucleoproteins through Receptor Mediated Endocytosis

Development of a Nitric Oxide-Responsive Labeling Reagent for Proteome Analysis of Live Cells

PROTAC-Mediated Degradation of Bruton’s Tyrosine Kinase Is Inhibited by Covalent Binding

GLI1-Inducible Glucuronidation Targets a Broad Spectrum of Drugs

Directed Evolution of Split APEX2 Peroxidase

A Unified Framework for the Incorporation of Bioorthogonal Compound Exposure Probes within Biological Compartments

Reverse Chemical Proteomics Identifies an Unanticipated Human Target of the Antimalarial Artesunate

Regulatory Mechanisms of the Mucin-Like Region on Herpes Simplex Virus during Cellular Attachment

Biosynthesis and Chemical Applications of Thioamides

SPR-Measured Dissociation Kinetics of PROTAC Ternary Complexes Influence Target Degradation Rate

An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing Receptor

An Isotope-Coded Photocleavable Probe for Quantitative Profiling of Protein O-GlcNAcylation

A Guanidine-Based Synthetic Compound Suppresses Angiogenesis via Inhibition of Acid Ceramidase

Gap-Junction-Dependent Labeling of Nascent Proteins in Multicellular Networks

High Sensitivity of Human Translesion DNA Synthesis Polymerase κ to Variation in O6-Carboxymethylguanine Structures

Peptidoglycan Metabolite Photoaffinity Reporters Reveal Direct Binding to Intracellular Pattern Recognition Receptors and Arf GTPases

Salinipeptins: Integrated Genomic and Chemical Approaches Reveal Unusual d-Amino Acid-Containing Ribosomally Synthesized and Post-Translationally Modified Peptides (RiPPs) from a Great Salt Lake Streptomyces sp.

Crystal Structures of Fumarate Hydratases from Leishmania major in a Complex with Inhibitor 2-Thiomalate

Targeting Base Excision Repair Glycosylases with DNA Containing Transition State Mimics Prepared via Click Chemistry

Transient Kinetics Reveal Mechanism and Voltage Dependence of Inhibitor and Substrate Binding to Glutamate Transporters

Structure of Sesquisabinene Synthase 1, a Terpenoid Cyclase That Generates a Strained [3.1.0] Bridged-Bicyclic Product

Unique Polypharmacology Nuclear Receptor Modulator Blocks Inflammatory Signaling Pathways

Novel Antimycobacterial Compounds Suppress NAD Biogenesis by Targeting a Unique Pocket of NaMN Adenylyltransferase

The Lasso Peptide Siamycin-I Targets Lipid II at the Gram-Positive Cell Surface

An Ancient Peptide Family Buried within Vicilin Precursors

©2008-2020 OALib, Inc | Public user content licensed CC-BY 4.0 unless otherwise specified. OALib ISSN Online: 2333-9721 OALib ISSN Print: 2333-9705