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OALib Journal期刊
ISSN: 2333-9721
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A Metastable Contact and Structural Disorder in the Estrogen Receptor Transactivation Domain
Structural Insights into Stimulation of Ash1L's H3K36 Methyltransferase Activity through Mrg15 Binding
Molecular Dissection of the Intrinsically Disordered Estrogen Receptor Alpha-NTD
How Natural Killer Cell Receptors Stick to Cell–Cell Adhesion Proteins
How Structural Biologists and the Protein Data Bank Contributed to Recent FDA New Drug Approvals
Helix Cracking Regulates the Critical Interaction between RetS and GacS in Pseudomonas aeruginosa
X-Ray Structure of Human Sulfide:Quinone Oxidoreductase: Insights into the Mechanism of Mitochondrial Hydrogen Sulfide Oxidation
Structures of the PKA RIα Holoenzyme with the FLHCC Driver J-PKAcα or Wild-Type PKAcα
Tertiary Structural Motif Sequence Statistics Enable Facile Prediction and Design of Peptides that Bind Anti-apoptotic Bfl-1 and Mcl-1
Infectivity of Dengue Virus Serotypes 1 and 2 Is Correlated with E-Protein Intrinsic Dynamics but Not to Envelope Conformations
The Structure of the SPOP-Pdx1 Interface Reveals Insights into the Phosphorylation-Dependent Binding Regulation
A Multi-model Approach to Assessing Local and Global Cryo-EM Map Quality
Caught in the Open: A Domain Insertion of M. tuberculosis Gyrase Suppresses ATPase Dimerization
Structural and Functional Characterization of Ubiquitin Variant Inhibitors of USP15
A Centipede Toxin Family Defines an Ancient Class of CSαβ Defensins
Structural Basis of H+-Dependent Conformational Change in a Bacterial MATE Transporter
MT1-MMP Binds Membranes by Opposite Tips of Its β Propeller to Position It for Pericellular Proteolysis
Mechanism of Enhanced Immature Dengue Virus Attachment to Endosomal Membrane Induced by prM Antibody
Dewetting Controls Plant Hormone Perception and Initiation of Drought Resistance Signaling
The Structure of HPK1 Kinase Domain: To Boldly Go Where No Immuno-Oncology Drugs Have Gone Before
The Different Effects of Substrates and Nucleotides on the Complex Formation of ABC Transporters
De Novo Structural Pattern Mining in Cellular Electron Cryotomograms
Defining a Canonical Ligand-Binding Pocket in the Orphan Nuclear Receptor Nurr1
Non-syndromic Mitral Valve Dysplasia Mutation Changes the Force Resilience and Interaction of Human Filamin A
The Small β-Barrel Domain: A Survey-Based Structural Analysis
Structures of Ebola and Reston Virus VP35 Oligomerization Domains and Comparative Biophysical Characterization in All Ebolavirus Species
Hematopoietic Progenitor Kinase-1 Structure in a Domain-Swapped Dimer
Conformational Changes in the Cytoplasmic Region of KIR3DL1 upon Interaction with SHP-2
Species-Specific Functional Regions of the Green Alga Gamete Fusion Protein HAP2 Revealed by Structural Studies
Single-Unit Imaging of Membrane Protein-Embedded Nanodiscs from Two Oriented Sides by High-Speed Atomic Force Microscopy
Structural Survey of Broadly Neutralizing Antibodies Targeting the HIV-1 Env Trimer Delineates Epitope Categories and Characteristics of Recognition
Structure of Calcarisporiella thermophila Hsp104 Disaggregase that Antagonizes Diverse Proteotoxic Misfolding Events
Joachim Frank's Binding with the Ribosome
HIV-1 Reverse Transcriptase: A Metamorphic Protein with Three Stable States
Advancing Chemokine GPCR Structure Based Drug Discovery
Novel Insights into Peptide Binding and Conformational Dynamics of UHRF1
Effector Specificity Mechanisms of Rab35 GTPase
Characterization of MCU-Binding Proteins MCUR1 and CCDC90B — Representatives of a Protein Family Conserved in Prokaryotes and Eukaryotic Organelles
Selection and Characterization of Artificial Proteins Targeting the Tubulin α Subunit
Affinity Improvement of a Cancer-Targeted Antibody through Alanine-Induced Adjustment of Antigen-Antibody Interface
Cholesterol Interaction Sites on the Transmembrane Domain of the Hedgehog Signal Transducer and Class F G Protein-Coupled Receptor Smoothened
Rab35/ACAP2 and Rab35/RUSC2 Complex Structures Reveal Molecular Basis for Effector Recognition by Rab35 GTPase
Architecture and Evolution of Blade Assembly in β-propeller Lectins
Collection of Continuous Rotation MicroED Data from Ion Beam-Milled Crystals of Any Size
Unleashing the Power of ASH1L Methyltransferase
Structural Basis for the Dual Substrate Specificity of DOCK7 Guanine Nucleotide Exchange Factor
The Plasticity of Molecular Interactions Governs Bacterial Microcompartment Shell Assembly
Structure of the UHRF1 Tandem Tudor Domain Bound to a Methylated Non-histone Protein, LIG1, Reveals Rules for Binding and Regulation
Structure-Guided Exploration of SDS22 Interactions with Protein Phosphatase PP1 and the Splicing Factor BCLAF1
Structural Basis for the Activation of the Deubiquitinase Calypso by the Polycomb Protein ASX
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