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OALib Journal期刊
ISSN: 2333-9721
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ISSN Print: 1530-0307

ISSN Online:

主页: https://www.nature.com/labinvest

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Inhibition of prolyl hydroxylase domain (PHD) by JTZ-951 reduces obesity-related diseases in the liver, white adipose tissue, and kidney in mice with a high-fat diet

Human relaxin-2 attenuates hepatic steatosis and fibrosis in mice with non-alcoholic fatty liver disease

Therapeutic potential of PLK1 inhibition in triple-negative breast cancer

Endotoxemia-induced endothelial fibrosis inhibition improves hypotension, tachycardia, multiple organ dysfunction syndrome, cytokine response, oxidative stress, and survival

Vascular changes in diabetic retinopathy—a longitudinal study in the Nile rat

N-terminal sequences in matrin 3 mediate phase separation into droplet-like structures that recruit TDP43 variants lacking RNA binding elements

Pirfenidone prevents and reverses hepatic insulin resistance and steatohepatitis by polarizing M2 macrophages

Autophagy-related 7 modulates tumor progression in triple-negative breast cancer

Potential MMP2-mediated availability of HLA binding, mutant ECM peptides reflects better melanoma survival rates and greater T-cell infiltrates

Non-cell autonomous modulation of tyrosine hydroxylase by HMGB1 released from astrocytes in an acute MPTP-induced Parkinsonian mouse model

Repression of miR-135b-5p promotes metastasis of early-stage breast cancer by regulating downstream target SDCBP

CD271 is a negative prognostic factor and essential for cell proliferation in lung squamous cell carcinoma

IL-1α and IL-1β promote NOD2-induced immune responses by enhancing MAPK signaling

Mesenchyme-specific deletion of Tgf-β1 in the embryonic lung disrupts branching morphogenesis and induces lung hypoplasia

Optimized cultivation of porcine choroid plexus epithelial cells, a blood–cerebrospinal fluid barrier model, for studying granulocyte transmigration

Micheliolide ameliorates renal fibrosis by suppressing the Mtdh/BMP/MAPK pathway

Repeat-associated non-AUG (RAN) translation: insights from pathology

B7H3 regulates differentiation and serves as a potential biomarker and theranostic target for human glioblastoma

Mitochondrial localization of PABPN1 in oculopharyngeal muscular dystrophy

Activation of death-associated protein kinase 1 promotes neutrophil apoptosis to accelerate inflammatory resolution in acute respiratory distress syndrome

False-positive pathology: improving reproducibility with the next generation of pathologists

Dynamic signature of lymphangiogenesis during acute kidney injury and chronic kidney disease

Lipoprotein modulation of proteinuric renal injury

p17 from HIV induces brain endothelial cell angiogenesis through EGFR-1-mediated cell signalling activation

The cofilin phosphatase slingshot homolog 1 restrains angiotensin II-induced vascular hypertrophy and fibrosis in vivo

BMP9-induced osteoblastic differentiation requires functional Notch signaling in mesenchymal stem cells

First trimester placental endothelial cells from pregnancies with abnormal uterine artery Doppler are more sensitive to apoptotic stimuli

Overexpression of KLF14 protects against immune-mediated hepatic injury in mice

T-cell trafficking plays an essential role in tumor immunity

Effect of SEPT6 on the biological behavior of hepatic stellate cells and liver fibrosis in rats and its mechanism

Multiplexed, high-throughput measurements of cell contraction and endothelial barrier function

Mitochondrial pyruvate carrier 1 functions as a tumor suppressor and predicts the prognosis of human renal cell carcinoma

Activation of brown adipose tissue enhances the efficacy of caloric restriction for treatment of nonalcoholic steatohepatitis

Characterization of immune cell subtypes in three commonly used mouse strains reveals gender and strain-specific variations

Overexpression of HIF-1α contributes to melphalan resistance in multiple myeloma cells by activation of ERK1/2, Akt, and NF-κB

Nondestructive, multiplex three-dimensional mapping of immune infiltrates in core needle biopsy

Lysyl oxidase enzymes mediate TGF-β1-induced fibrotic phenotypes in human skin-like tissues

Luminex-based quantification of Alzheimer’s disease neuropathologic change in formalin-fixed post-mortem human brain tissue

The oncogenic RNA-binding protein SRSF1 regulates LIG1 in non-small cell lung cancer

Trends in the characteristics of human functional genomic data on the gene expression omnibus, 2001–2017

O-GlcNAcylation of GLI transcription factors in hyperglycemic conditions augments Hedgehog activity

Sensory nerve supports epithelial stem cell function in healing of corneal epithelium in mice: the role of trigeminal nerve transient receptor potential vanilloid 4

Heparin-binding epidermal growth factor (HB-EGF) drives EMT in patients with COPD: implications for disease pathogenesis and novel therapies

Western-type diet differentially modulates osteoblast, osteoclast, and lipoblast differentiation and activation in a background of APOE deficiency

Vitamin D protects human melanocytes against oxidative damage by activation of Wnt/β-catenin signaling

Poldip2 knockdown inhibits vascular smooth muscle proliferation and neointima formation by regulating the expression of PCNA and p21

Abrogation of transforming growth factor-β-induced tissue fibrosis in mice with a global genetic deletion of Nox4

The role of Ca2+ in acid-sensing ion channel 1a-mediated chondrocyte pyroptosis in rat adjuvant arthritis

miR-608 and miR-4513 significantly contribute to the prognosis of lung adenocarcinoma treated with EGFR-TKIs

Differential bronchial epithelial response regulated by ΔNp63: a functional understanding of the epithelial shedding found in asthma

©2008-2020 OALib, Inc | Public user content licensed CC-BY 4.0 unless otherwise specified. OALib ISSN Online: 2333-9721 OALib ISSN Print: 2333-9705