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OALib Journal期刊
ISSN: 2333-9721
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ISSN Print: 2092-6413

ISSN Online:

主页: https://www.nature.com/emm

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MiR-34a and miR-34b/c have distinct effects on the suppression of lung adenocarcinomas

Disturbed homocysteine metabolism is associated with cancer

Phase II trial of VEGFR2 inhibitor apatinib for metastatic sarcoma: focus on efficacy and safety

Deacetylation of CHK2 by SIRT1 protects cells from oxidative stress-dependent DNA damage response

Development of a patient-derived xenograft model of glioblastoma via intravitreal injection in mice

SIRT1 inhibits monocyte adhesion to the vascular endothelium by suppressing Mac-1 expression on monocytes

Myeloid cell-specific sirtuin 6 deficiency delays wound healing in mice by modulating inflammation and macrophage phenotypes

Ninjurin1 positively regulates osteoclast development by enhancing the survival of prefusion osteoclasts

Nobiletin ameliorates hepatic ischemia and reperfusion injury through the activation of SIRT-1/FOXO3a-mediated autophagy and mitochondrial biogenesis

Blocking TBK1 alleviated radiation-induced pulmonary fibrosis and epithelial-mesenchymal transition through Akt-Erk inactivation

Lysophosphatidic acid increases mesangial cell proliferation in models of diabetic nephropathy via Rac1/MAPK/KLF5 signaling

Extracellular vesicles in onco-nephrology

Mechanism of the natural product moracin-O derived MO-460 and its targeting protein hnRNPA2B1 on HIF-1α inhibition

Extracellular vesicle-based therapeutics: natural versus engineered targeting and trafficking

NF-κB-responsive miR-155 induces functional impairment of vascular smooth muscle cells by downregulating soluble guanylyl cyclase

Estrogen receptor α in T cells suppresses follicular helper T cell responses and prevents autoimmunity

SMURF1-mediated ubiquitination of ARHGAP26 promotes ovarian cancer cell invasion and migration

Estrogen negatively regulates the renal epithelial sodium channel (ENaC) by promoting Derlin-1 expression and AMPK activation

In vivo transduction of ETV2 improves cardiac function and induces vascular regeneration following myocardial infarction

Adipose sirtuin 6 drives macrophage polarization toward M2 through IL-4 production and maintains systemic insulin sensitivity in mice and humans

Mass spectrometry-based proteome profiling of extracellular vesicles and their roles in cancer biology

LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18) distinctly regulate neutrophil extravasation through hotspots I and II

Rbfox2 dissociation from stress granules suppresses cancer progression

Beyond EGFR inhibition: multilateral combat strategies to stop the progression of head and neck cancer

Systems biology approaches to investigating the roles of extracellular vesicles in human diseases

High-resolution respirometry in human endomyocardial biopsies shows reduced ventricular oxidative capacity related to heart failure

Connectivity map identifies luteolin as a treatment option of ischemic stroke by inhibiting MMP9 and activation of the PI3K/Akt signaling pathway

Restoration of FVIII expression by targeted gene insertion in the FVIII locus in hemophilia A patient-derived iPSCs

Luteolin promotes apoptotic cell death via upregulation of Nrf2 expression by DNA demethylase and the interaction of Nrf2 with p53 in human colon cancer cells

P110β in the ventromedial hypothalamus regulates glucose and energy metabolism

Inhibition of β-site amyloid precursor protein cleaving enzyme 1 and cholinesterases by pterosins via a specific structure？activity relationship with a strong BBB permeability

Notch1 promotes the pericyte-myofibroblast transition in idiopathic pulmonary fibrosis through the PDGFR/ROCK1 signal pathway

Extracellular signal-regulated kinase 5 increases radioresistance of lung cancer cells by enhancing the DNA damage response

Hypermethylation of Frizzled1 is associated with Wnt/β-catenin signaling inactivation in mesenchymal stem cells of patients with steroid-associated osteonecrosis

Phosphoregulation of the oncogenic protein regulator of cytokinesis 1 (PRC1) by the atypical CDK16/CCNY complex

Direct conversion of fibroblasts to osteoblasts as a novel strategy for bone regeneration in elderly individuals

Allogeneic ADSCs induce CD8 T cell-mediated cytotoxicity and faster cell death after exposure to xenogeneic serum or proinflammatory cytokines

Mitochondrial superoxide dismutase 2 mediates γ-irradiation-induced cancer cell invasion

Epigenetic analysis in rheumatoid arthritis synoviocytes

Downregulation of lysyl oxidase and lysyl oxidase-like protein 2 suppressed the migration and invasion of trophoblasts by activating the TGF-β/collagen pathway in preeclampsia

Diagnosis of Alzheimer’s disease utilizing amyloid and tau as fluid biomarkers

Unilateral ureteral obstruction causes gut microbial dysbiosis and metabolome disorders contributing to tubulointerstitial fibrosis

Exploiting the message from cancer: the diagnostic value of extracellular vesicles for clinical applications

A cell-penetrating peptide blocks Toll-like receptor-mediated downstream signaling and ameliorates autoimmune and inflammatory diseases in mice

PAK4 signaling in health and disease: defining the PAK4–CREB axis

Kynurenine 3-monooxygenase is a critical regulator of renal ischemia–reperfusion injury

A novel and safe small molecule enhances hair follicle regeneration by facilitating metabolic reprogramming

Melatonin protects endothelial progenitor cells against AGE-induced apoptosis via autophagy flux stimulation and promotes wound healing in diabetic mice

Elevated extracellular calcium ions promote proliferation and migration of mesenchymal stem cells via increasing osteopontin expression

FAM46B inhibits cell proliferation and cell cycle progression in prostate cancer through ubiquitination of β-catenin

©2008-2020 OALib, Inc | Public user content licensed CC-BY 4.0 unless otherwise specified. OALib ISSN Online: 2333-9721 OALib ISSN Print: 2333-9705