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ISSN: 2333-9721
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ISSN Print: 2095-6231

ISSN Online:

主页: https://www.nature.com/boneres

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Hypoxia-inducible factor 2α is a negative regulator of osteoblastogenesis and bone mass accrual

Characterization of a novel murine Sost ERT2 Cre model targeting osteocytes

Engineering osteoblastic metastases to delineate the adaptive response of androgen-deprived prostate cancer in the bone metastatic microenvironment

Connexin 43 hemichannels protect bone loss during estrogen deficiency

Pathological mechanisms and therapeutic outlooks for arthrofibrosis

NOTUM inhibition increases endocortical bone formation and bone strength

Controlling hypoxia-inducible factor-2α is critical for maintaining bone homeostasis in mice

Collagen type II suppresses articular chondrocyte hypertrophy and osteoarthritis progression by promoting integrin β1？SMAD1 interaction

Efficacy of an orally active small-molecule inhibitor of RANKL in bone metastasis

DMP1 prevents osteocyte alterations, FGF23 elevation and left ventricular hypertrophy in mice with chronic kidney disease

Activation of mTORC1 in subchondral bone preosteoblasts promotes osteoarthritis by stimulating bone sclerosis and secretion of CXCL12

Long noncoding RNAs: a missing link in osteoporosis

Exosomes—the enigmatic regulators of bone homeostasis

Dietary fat-associated osteoarthritic chondrocytes gain resistance to lipotoxicity through PKCK2/STAMP2/FSP27

Mandible exosomal ssc-mir-133b regulates tooth development in miniature swine via endogenous apoptosis

Super enhancer inhibitors suppress MYC driven transcriptional amplification and tumor progression in osteosarcoma

Ciliary parathyroid hormone signaling activates transforming growth factor-β to maintain intervertebral disc homeostasis during aging

Aberrant activation of latent transforming growth factor-β initiates the onset of temporomandibular joint osteoarthritis

Paracrine and endocrine actions of bone—the functions of secretory proteins from osteoblasts, osteocytes, and osteoclasts

Enhancer variants reveal a conserved transcription factor network governed by PU.1 during osteoclast differentiation

IGF-I induced phosphorylation of PTH receptor enhances osteoblast to osteocyte transition

CHIP regulates bone mass by targeting multiple TRAF family members in bone marrow stromal cells

Omentin-1 prevents inflammation-induced osteoporosis by downregulating the pro-inflammatory cytokines

Oxidized phospholipids are ligands for LRP6

Rheumatoid arthritis: pathological mechanisms and modern pharmacologic therapies

RANKL signaling in bone marrow mesenchymal stem cells negatively regulates osteoblastic bone formation

R-spondin-2 is a Wnt agonist that regulates osteoblast activity and bone mass

Gαs signaling controls intramembranous ossification during cranial bone development by regulating both Hedgehog and Wnt/β-catenin signaling

Engineering 3D approaches to model the dynamic microenvironments of cancer bone metastasis

mTOR signaling in skeletal development and disease

Advanced smart biomaterials and constructs for hard tissue engineering and regeneration

Molecularly specific detection of bacterial lipoteichoic acid for diagnosis of prosthetic joint infection of the bone

A peptide containing the receptor binding site of insulin-like growth factor binding protein-2 enhances bone mass in ovariectomized rats

NUMB maintains bone mass by promoting degradation of PTEN and GLI1 via ubiquitination in osteoblasts

The art of building bone: emerging role of chondrocyte-to-osteoblast transdifferentiation in endochondral ossification

Histone demethylase LSD1 regulates bone mass by controlling WNT7B and BMP2 signaling in osteoblasts

Enhanced cortical bone expansion in Lgals3-deficient mice during aging

Transforming growth factor-β in stem cells and tissue homeostasis

Mechanically induced Ca2+ oscillations in osteocytes release extracellular vesicles and enhance bone formation

SHP2 regulates skeletal cell fate by modifying SOX9 expression and transcriptional activity

Nucleic acids and analogs for bone regeneration

YAP promotes osteogenesis and suppresses adipogenic differentiation by regulating β-catenin signaling

Alpl prevents bone ageing sensitivity by specifically regulating senescence and differentiation in mesenchymal stem cells

Biomimetic delivery of signals for bone tissue engineering

BMP-IHH-mediated interplay between mesenchymal stem cells and osteoclasts supports calvarial bone homeostasis and repair

Lrp1 in osteoblasts controls osteoclast activity and protects against osteoporosis by limiting PDGF–RANKL signaling

Bone loss from Wnt inhibition mitigated by concurrent alendronate therapy

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