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OALib Journal期刊
ISSN: 2333-9721
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ISSN Print: 1476-5500

ISSN Online:

主页: https://www.nature.com/cgt

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Salmonella-mediated therapy targeting indoleamine 2, 3-dioxygenase 1 (IDO) activates innate immunity and mitigates colorectal cancer growth

Dendritic cell vaccination plus low-dose doxorubicin for the treatment of spontaneous canine hemangiosarcoma

Transferrin receptor-involved HIF-1 signaling pathway in cervical cancer

Intratumoral expression using a NFkB-based promoter enhances IL12 antitumor efficacy

Expression profile and bioinformatics analysis of COMMD10 in BALB/C mice and human

c-Myc induced upregulation of long non-coding RNA SNHG16 enhances progression and carcinogenesis in oral squamous cell carcinoma

Clinical characteristics and prognostic analysis of multiple primary malignant neoplasms in patients with lung cancer

The circINTS4/miR-146b/CARMA3 axis promotes tumorigenesis in bladder cancer

High IFITM3 expression predicts adverse prognosis in acute myeloid leukemia

Use of polymeric CXCR4 inhibitors as siRNA delivery vehicles for the treatment of acute myeloid leukemia

Prognosis value of RBBP8 expression in plasma cell myeloma

BET inhibitor I-BET151 sensitizes GBM cells to temozolomide via PUMA induction

Gene therapy for castration-resistant prostate cancer cells using JC polyomavirus-like particles packaged with a PSA promoter driven-suicide gene

Dissecting the functional role of microRNA 21 in osteosarcoma

Enhanced noninvasive imaging of oncology models using the NIS reporter gene and bioluminescence imaging

High expression of UBE2T predicts poor prognosis and survival in multiple myeloma

Preferential sensitivity to HDAC inhibitors in tumors with CREBBP mutation

Prognostic significance of PAK family kinases in acute myeloid leukemia

Schwannoma gene therapy by adeno-associated virus delivery of the pore-forming protein Gasdermin-D

CTGF expression is indicative of better survival rates in patients with medulloblastoma

Overexpression of SOCS3 mediated by adenovirus vector in mouse and human castration-resistant prostate cancer cells increases the sensitivity to NK cells in vitro and in vivo

Human marrow stromal cells secrete microRNA-375-containing exosomes to regulate glioma progression

JAK/STAT inhibition with ruxolitinib enhances oncolytic virotherapy in non-small cell lung cancer models

Autologous CD19-directed chimeric antigen receptor-T cell is an effective and safe treatment to refractory or relapsed diffuse large B-cell lymphoma

Safety and efficacy of oncolytic HSV-1 G207 inoculated into the cerebellum of mice

Down-regulation of 14-3-3zeta reduces proliferation and increases apoptosis in human glioblastoma

Downregulation of miR-152 contributes to DNMT1-mediated silencing of SOCS3/SHP-1 in non-Hodgkin lymphoma

Efficient tumor transduction and antitumor efficacy in experimental human osteosarcoma using retroviral replicating vectors

Upregulation of microRNA-3129 suppresses epithelial ovarian cancer through CD44

Phase I trial of intravenous Ad5CRT in patients with liver metastasis of gastrointestinal cancers

Tissue-specific induced DNA methyltransferase 1 (Dnmt1) in endocrine pancreas by RCAS-TVA-based somatic gene transfer system promotes β-cell proliferation

Inhibitor of growth 3 induces cell death by regulating cell proliferation, apoptosis and cell cycle arrest by blocking the PI3K/AKT pathway

Targeting GD2-positive glioblastoma by chimeric antigen receptor empowered mesenchymal progenitors

miR-182 regulates trastuzumab resistance by targeting MET in breast cancer cells

Endostatin gene therapy delivered by attenuated Salmonella typhimurium in murine tumor models

MicroRNA-122 negatively associates with peroxiredoxin-II expression in human gefitinib-resistant lung cancer stem cells

GINS2 promotes cell proliferation and inhibits cell apoptosis in thyroid cancer by regulating CITED2 and LOXL2

LncRNA SNHG14 promotes inflammatory response induced by cerebral ischemia/reperfusion injury through regulating miR-136-5p /ROCK1

Enhanced expressions of FHL2 and iASPP predict poor prognosis in acute myeloid leukemia

Serum exosomes contain ECRG4 mRNA that suppresses tumor growth via inhibition of genes involved in inflammation, cell proliferation, and angiogenesis

Increasing the bactofection capacity of a mammalian expression vector by removal of the f1 ori

Reviewer recognition

Mutational spectrum and prognostic stratification of intermediate-risk acute myeloid leukemia

Overexpression of PDK2 and PDK3 reflects poor prognosis in acute myeloid leukemia

Dual-vector prodrug activator gene therapy using retroviral replicating vectors

Inhibition of oncogenic cap-dependent translation by 4EGI-1 reduces growth, enhances chemosensitivity and alters genome-wide translation in non-small cell lung cancer

High expression levels of SMAD3 and SMAD7 at diagnosis predict poor prognosis in acute myeloid leukemia patients undergoing chemotherapy

Inducible Caspase9-mediated suicide gene for MSC-based cancer gene therapy

miR-140-5p inhibits the proliferation and enhances the efficacy of doxorubicin to breast cancer stem cells by targeting Wnt1

Adenovirus-mediated transfer of HPV 16 E6/E7 antisense RNA combined with cisplatin inhibits cellular growth and induces apoptosis in HPV-positive head and neck cancer cells

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