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OALib Journal期刊
ISSN: 2333-9721
费用:99美元
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ISSN Print: 1476-5594
ISSN Online:
主页:
https://www.nature.com/onc
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AKIP1 promotes early recurrence of hepatocellular carcinoma through activating the Wnt/β-catenin/CBP signaling pathway
MST1R kinase accelerates pancreatic cancer progression via effects on both epithelial cells and macrophages
Cancer-associated fibroblasts promote prostate cancer malignancy via metabolic rewiring and mitochondrial transfer
PARI (PARPBP) suppresses replication stress-induced myeloid differentiation in leukemia cells
Androgen receptor-modulatory microRNAs provide insight into therapy resistance and therapeutic targets in advanced prostate cancer
Upregulated claudin-1 expression promotes colitis-associated cancer by promoting β-catenin phosphorylation and activation in Notch/p-AKT-dependent manner
MYB regulates the DNA damage response and components of the homology-directed repair pathway in human estrogen receptor-positive breast cancer cells
The anti-malarial drug chloroquine sensitizes oncogenic NOTCH1 driven human T-ALL to γ-secretase inhibition
LncRNA NORAD is repressed by the YAP pathway and suppresses lung and breast cancer metastasis by sequestering S100P
Impaired microRNA processing by DICER1 downregulation endows thyroid cancer with increased aggressiveness
Mitochondrial fission-induced mtDNA stress promotes tumor-associated macrophage infiltration and HCC progression
AKT drives SOX2 overexpression and cancer cell stemness in esophageal cancer by protecting SOX2 from UBR5-mediated degradation
Extracellular vesicle-dependent effect of RNA-binding protein IGF2BP1 on melanoma metastasis
Targeting AU-rich element-mediated mRNA decay with a truncated active form of the zinc-finger protein TIS11b/BRF1 impairs major hallmarks of mammary tumorigenesis
LPLUNC1 stabilises PHB1 by counteracting TRIM21-mediated ubiquitination to inhibit NF-κB activity in nasopharyngeal carcinoma
BET bromodomain inhibition blocks the function of a critical AR-independent master regulator network in lethal prostate cancer
NMIIA promotes tumor growth and metastasis by activating the Wnt/β-catenin signaling pathway and EMT in pancreatic cancer
Axitinib exposure triggers endothelial cells senescence through ROS accumulation and ATM activation
Addiction to DUSP1 protects JAK2V617F-driven polycythemia vera progenitors against inflammatory stress and DNA damage, allowing chronic proliferation
Pathogenic mutations in neurofibromin identifies a leucine-rich domain regulating glioma cell invasiveness
Non-canonical HIF-1 stabilization contributes to intestinal tumorigenesis
H19 lncRNA identified as a master regulator of genes that drive uterine leiomyomas
Endogenous interaction profiling identifies DDX5 as an oncogenic coactivator of transcription factor Fra-1
UHRF1 promotes renal cell carcinoma progression through epigenetic regulation of TXNIP
GPNMB augments Wnt-1 mediated breast tumor initiation and growth by enhancing PI3K/AKT/mTOR pathway signaling and β-catenin activity
Quaking orchestrates a post-transcriptional regulatory network of endothelial cell cycle progression critical to angiogenesis and metastasis
Cancer stem cell self-renewal as a therapeutic target in human oral cancer
The miR-186-3p/EREG axis orchestrates tamoxifen resistance and aerobic glycolysis in breast cancer cells
Non-murine models to investigate tumor-immune interactions in head and neck cancer
Identification and characterization of two novel oncogenic mTOR mutations
Inhibition of geranylgeranyl diphosphate synthase is a novel therapeutic strategy for pancreatic ductal adenocarcinoma
Distinctive requirement of PKCε in the control of Rho GTPases in epithelial and mesenchymally transformed lung cancer cells
Low doses of decitabine improve the chemotherapy efficacy against basal-like bladder cancer by targeting cancer stem cells
FDPS cooperates with PTEN loss to promote prostate cancer progression through modulation of small GTPases/AKT axis
ROR1-CAVIN3 interaction required for caveolae-dependent endocytosis and pro-survival signaling in lung adenocarcinoma
LINC00162 confers sensitivity to 5-Aza-2′-deoxycytidine via modulation of an RNA splicing protein, HNRNPH1
Dissecting mechanisms of resistance to targeted drug combination therapy in human colorectal cancer
Tumor-associated macrophage-secreted 14-3-3ζ signals via AXL to promote pancreatic cancer chemoresistance
JMJD2 promotes acquired cisplatin resistance in non-small cell lung carcinoma cells
YAP-dependent induction of UHMK1 supports nuclear enrichment of the oncogene MYBL2 and proliferation in liver cancer cells
piRNA-823 delivered by multiple myeloma-derived extracellular vesicles promoted tumorigenesis through re-educating endothelial cells in the tumor environment
PDGFR-induced autocrine SDF-1 signaling in cancer cells promotes metastasis in advanced skin carcinoma
A high-throughput screen identifies the long non-coding RNA DRAIC as a regulator of autophagy
Microenvironmental oxygen pressure orchestrates an anti- and pro-tumoral γδ T cell equilibrium via tumor-derived exosomes
miR-4516 predicts poor prognosis and functions as a novel oncogene via targeting PTPN14 in human glioblastoma
NOVA1 directs PTBP1 to hTERT pre-mRNA and promotes telomerase activity in cancer cells
Targeting the α4–α5 dimerization interface of K-RAS inhibits tumor formation in vivo
An evolving story of the metastatic voyage of ovarian cancer cells: cellular and molecular orchestration of the adipose-rich metastatic microenvironment
Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis
HSP110 translocates to the nucleus upon genotoxic chemotherapy and promotes DNA repair in colorectal cancer cells
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