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OALib Journal期刊
ISSN: 2333-9721
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ISSN Print: 1848-7718

ISSN Online:

主页: https://hrcak.srce.hr/admet

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Prediction of aqueous intrinsic solubility of druglike molecules using Random Forest regression trained with Wiki-pS0 database

Avdeef, Alex

Validated HPLC method for quantification of copanlisib in mice plasma: application to a pharmacokinetic study

Bestha, Ram Murthi,Daram, Prasanthi,Dittakavi, Sreekanth,Kurakula, Pavan Kumar,Mullangi, Ramesh,Trivedi, Ravi Kumar,Zainuddin, Mohd,Zakkula, Ashok

Estimation of the octanol-water distribution coefficient of basic compounds by a cationic microemulsion electrokinetic chromatography system

Amézqueta, Susana,Fernández-Pumarega, Alejandro,Fuguet, Elisabet,Martín-Sanz, Belén,Rosés, Marti

Optimization of experimental conditions for skin-PAMPA measurements

Fuguet, Elisabet,Port, Adriana,Rosés, Martí,Soriano-Meseguer, Sara

Revisiting the application of Immobilized Artificial Membrane (IAM) chromatography to estimate in vivo distribution properties of drug discovery compounds based on the model of marketed drugs

Anderson, Scott,Bunally, Shenaz,Rava, Silvia,Valko, Klara

Nanogels as nanocarriers for drug delivery: A review

Naik, Jitendra,Narkhede, Jitendra,Rajput, Rahul

Molecular docking studies of salubrinal and its analogs as inhibitors of the GADD34:PP1 enzyme

Kharchenko, Aleksandr V.,Kiselev, Vadym V.,Okhtina, Oxana V.,Pokotylo, Ihor O.,Zadorozhnii, Pavlo V.

A physiologically-based pharmacokinetic model of oseltamivir phosphate and its carboxylate metabolite for rats and humans

Gao, Guanghua,Law, Francis,Mak, Nai Ki,Wong, Ricky Ngok Shun,Yang, Mildred Sze Ming

Induced fit for cytochrome P450 3A4 based on molecular dynamics

Quiroga, Israel,Scior, Thomas

Physiologically based pharmacokinetic (PBPK) modeling and simulation in drug discovery and development

Khan, Ansar Ali,Shaik, Abdul Naveed

Permeation characteristics of tetracyclines in parallel artificial membrane permeation assay

Sugano, Kiyohiko,Yamauchi, Sachika

Quantitative structure-activity relationship to elucidate human CYP2A6 inhibition by organosulfur compounds

Camargo, Alejandra B.,Luco, Juan M.,Marchevsky, Eduardo J.,Ramirez, Daniela A.

NMR spectroscopy in drug discovery and development: Evaluation of physico-chemical properties

Zloh, Mire

Biophysical methods in early drug discovery

Davies, Gareth,Embrey, Kevin,Holdgate, Geoffrey,Milbradt, Alexander

Validated LC-ESI-MS/MS method for the determination of ivosidenib in 10 μL mice plasma: application to a pharmacokinetic study

Dittakavi, Sreekanth,Jairam, Ravi Kumar,Jat, Rakesh Kumar,Mallurwar, Sadanand Rangnathrao,Mullangi, Ramesh

Investigation of possible solubility and dissolution advantages of cocrystals, I: Aqueous solubility and dissolution rates of ketoconazole and its cocrystals as functions of pH

Serajuddin, Abu T.M.,Shah, Ankita V.,Vasoya, Jaydip M.

Physiologically-based pharmacokinetic simulations in pharmacotherapy: selection of the optimal administration route for exogenous melatonin

Manca, Davide,Savoca, Adriana

Prediction of ADME-Tox properties and toxicological endpoints of triazole fungicides used for cereals protection

Ciorsac, Alecu Aurel,Gridan, Ionu？ M？d？lin,Isvoran, Adriana

Applications of biophysical techniques in drug discovery and development

Verbi？, Tatjana

Bioenhancing effects of naringin on atorvastatin

Alvala, Ravi,Chiluka, Rajeswari,Mullangi, Ramesh,Pagilla, Balaraju,Pola, Ravi Kumar,Sama, Venkatesh

Multi-lab intrinsic solubility measurement reproducibility in CheqSol and shake-flask methods

Avdeef, Alex

Perspectives in solubility measurement and interpretation

Avdeef, Alex,Bergstr？m, Christel A.S.

Building in-house PBPK modelling tools for oral drug administration from literature information

Brogin, Giandomenico,Cesari, Nicola,Grandoni, Silvia,Magni, Paolo,Puccini, Paola

Nicotinic acid in nanocontainers. Encapsulation and release from ion exchangers

Altshuler, Heinrich,Altshuler, Olga,Lyrschikov, Sergey,Malyshenko, Natalya,Ostapova, Elena,Parshkov, Roman,Shkurenko, Galina

PKQuest: PBPK modeling of highly lipid soluble and extracellular solutes

Levitt, David

Block relevance (BR) analysis and polarity descriptors in property-based drug design

Caron, Giulia,Ermondi, Giuseppe

Erratum to the paper: In vitro membrane binding and protein binding (IAM MB/PB technology) to estimate in vivo distribution: applications in early drug discovery

Pudgeon, Charles,Teague, Simon,Valko, Klara

The role and impact of high throughput biomimetic measurements in drug discovery

Bunally, Shenaz,Young, Robert J.

Application of biomimetic HPLC to estimate lipophilicity, protein and phospholipid binding of potential peptide therapeutics

Beswick, Paul,Ivanova-Berndt, Gabriela,Kindey, Mark,Ko, Dorothy,Valko, Klara

Special issue devoted to the 6th IAPC Meeting: joint events comprising 6th World conference on physico-chemical methods in drug discovery and development and 3rd World conference on ADMET and DMPK

Mandi？, Zoran,Tam, Kin

Development and validation of a novel method for simultaneous quantification of enzalutamide, darolutamide and their active metabolites in mice dried blood spots using LC-MS/MS: application to pharmacokinetic study in mice

Mullangi, Ramesh,Saini, Neraj Kumar,Sulochana, Suresh P.,Zainuddin, Mohd

Feasibility of the estimation of octanol-water distribution coefficients of acidic drugs by microemulsion electrokinetic chromatography

Amézqueta, Susana,Fernández-Pumarega, Alejandro,Fuguet, Elisabet,Rosés, Marti

Evaluation of the interactions between human serum albumin (HSA) and warfarin or diflunisal by using molecular fluorescence using two approaches

Amézqueta, Susana,Beltrán, José Luis,Bolioli, Anna Maria,Ràfols, Clara

Use of low field NMR for the characterization of gels and biological tissues

Abrami, Michaela,Chiarappa, Gianluca,Farra, Rossella,Grassi, Gabriele,Grassi, Mario,Marizza, Paolo

In silico ADME in drug design – enhancing the impact

Ahlberg, Ernst,Greene, Nigel,Mogemark, Mickale,Noeske, Tobias,Oprisiu, Ioana,Watson, Edmund,Winiwarter, Susanne

Cellular membrane affinity chromatography (CMAC) in drug discovery from complex natural matrices

Ciesla, Lukasz,El Omri, Abdelfatteh,Stephen, Cayman

Subcellular localization of several structurally different tyrosine kinase inhibitors

Hitzerd, Sarina M.,Honeywell, Richard J.,Kathmann, G.A.M.,Peters, Godefridus J.

Dissolution rates of ciprofloxacin and its cocrystal with resorcinol

Fael, Hanan,Fuguet, Elisabet,Lee, Samuel,Outhwaite, Breeze,Ruiz, Rebeca,Ràfols, Clara

Cocrystal solubility-pH and drug solubilization capacity of sodium dodecyl sulfate – mass action model for data analysis and simulation to improve design of experiments

Avdeef, Alex

Lipophilicity determination of acidic compounds: MEEKC as a reliable high-throughput methodology

Redón, Lídia,Rosés, Martí,Subirats, Xavier

Animal model investigation suggests betamethasone alters the pharmacokinetics of amikacin

Amponsah, Seth Kwabena,Donkor, Ama Asiedua,Opuni, Kwabena Frimpong-Manso

The role of pharmacology in anticancer drug development

Govaerts, Anne-Sophie,Hendriks, Hans,Molecular Mechanism Group, for the EORTC- Pharmacology and,Peters, Godefridus

Immobilized artificial membrane chromatography: from medicinal chemistry to environmental sciences

Stergiopoulos, Chrysanthos,Tsantili-Kakoulidou, Anna,Tsopelas, Fotis

Estimation of skin permeation by liquid chromatography

Fuguet, Elisabet,Port, Adriana,Rosés, Martí,Soriano-Meseguer, Sara

In vitro biomimetic HPLC and in vivo characterisation of GM6, an endogenous regulator peptide drug candidate for amyotrophic lateral sclerosis

Evans, James,Kindy, Mark,Ko, Dorothy,Valko, Klara

Computational screens can speed up the discovery of pharmaceutical cocrystals

Hunter, Christopher,Prohens, Rafel

Chromatographic technique to support ADMET&DMPK in early drug discovery

Valko, Klara

Spectroscopic examination and release of microencapsulated oregano essential oil

Karakasidou, Panagiota,Nikolakakis, Ioannis,Partheniadis, Ioannis,Vergkizi, Souzan

Preclinical assessment of ulixertinib, a novel ERK1/2 inhibitor

Balakrishna, Vinod A,Bhamidipati, Ravi Kanth,Chandrasekhar, Devaraj V,Hiremath, Rakesh A,Mullangi, Ramesh,Police, Anitha,Raj, Anusha,Sulochana, Suresh P,Zainuddin, Mohd

©2008-2020 OALib, Inc | Public user content licensed CC-BY 4.0 unless otherwise specified. OALib ISSN Online: 2333-9721 OALib ISSN Print: 2333-9705