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SLAS DISCOVERY: Advancing Life Sciences R&D

ISSN Print: 2472-5552

ISSN Online: 2472-5560

主页: https://journals.sagepub.com/loi/jbxb

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Influence of Matrigel on Single

Alina Ciceu,Anca Dinischiotu,Anca Hermenean,Daniela Ionita,Hildegard Herman,Madalina Andreea Badea,Mihaela Balas

A General TR

Jacqueline L. Norris-Drouin,Justin M. Rectenwald,Kenneth H. Pearce,Lindsey I. James,P. Brian Hardy,Stephanie H. Cholensky,Stephen V. Frye

Confirmation of Selected Synergistic Cancer Drug Combinations Identified in an HTS Campaign and Exploration of Drug Efflux Transporter Contributions to the Mode of Synergy

Allen Xinwei Wang,David A. Close,Julie L. Eiseman,Paul A. Johnston,Philip E. Empey,Stanton J. Kochanek,Tongying Shun

OCTN: A Small Transporter Subfamily with Great Relevance to Human Pathophysiology, Drug Discovery, and Diagnostics

Cesare Indiveri,Lara Console,Lorena Pochini,Mariafrancesca Scalise,Michele Galluccio

A New Model of Sensorial Neuron

Antón L. Martínez,Javier Burgue？o,José Brea,Manuel Merlos,María Isabel Loza,Xavier Monroy

Development of a Bacterial Macroarray for the Rapid Screening of Targeted Antibody

Chengchao Ding,Dongpo Xu,Jie Li,Jing Pan,Jingxuan Qiu,Qi Zhang,Qing Liu,Qingli Dong,Xiang Wang,XuZhao Zhai,Yali Liu

Identification of Primary Natural Killer Cell Modulators by Chemical Library Screening with a Luciferase

David S. Wishart,Jean-Philippe Herbeuval,Laurie Besson,Nassima Bekaddour,Nicolas Pietrancosta,Nikaia Smith,Pierre-Olivier Vidalain,Rodolphe Alves de Sousa,Rupasri Mandal,Simon Hayek,Sébastien Nisole,Sébastien Viel,Thierry Walzer,Yves Jacob

Novel 2

Chee Onn Leong,Chun Wai Mai,Dedrick Soon Seng Song,Faridah Abas,Felicia Fei-Lei Chung,Khozirah Shaari,Kwok Wen Ng,Ling Wei Hii,Pei Jean Tan,Sze Wei Leong,Vyomesh Patel

Identification of Novel Mast Cell Activators Using Cell

Brandi T. Johnson-Weaver,Cliburn Chan,David M. Gooden,Gregory D. Sempowski,Hae Woong Choi,Heather E. Lynch,Herman F. Staats,Ivo D. Shterev,Jianling Shi,John K. Dickson,So Young Kim,Soman N. Abraham,Taylor J. Robinette

Enzyme–Inhibitor Interactions and a Simple, Rapid Method for Determining Inhibition Modality

P. Ann Boriack-Sjodin,Robert A. Copeland,Shane M. Buker

Transfer Learning with Deep Convolutional Neural Networks for Classifying Cellular Morphological Changes

Alexander Kensert,Ola Spjuth,Philip J. Harrison

Addressing Antimicrobial Resistance through New Medicinal and Synthetic Chemistry Strategies

Monika I. Konaklieva

Morphology

Kei Kanie,Kei Yoshida,Kenji Omori,Kiyoshi Ishikawa,Ryuji Kato

Development of a High

Brian Donovan,Derek D. Poore,Glenn Hofmann,Hongwei Qi,Hu Li,Lawrence A. Wolfe,Michael Fischer,Ming Jiang,Subhas Chakravorty,Thomas D. Sweitzer,Zining Wu

The Academic Pill: How Academia Contributes to Curing Diseases

Marc Bickle

Identification and Characterization of Inhibitors of a Neutral Amino Acid Transporter, SLC6A19, Using Two Functional Cell

Adam Belanger,Beirong Liang,Benjamin Coupland,Drew Tietz,Estelle Gefteas,Helen Klodnitsky,Jill Gregory,Kristen Randall,Oanh Smicker,Sanjay J. Danthi,Theresa A. Kuntzweiler

Identification of G

Brooke Swalm,Chad Chamberlin,Christine Andrews,Deborah A. Flusberg,Elliott B. Nickbarg,Graham F. Smith,Jennifer O’Neil,Noreen F. Rizvi,Patrick Curran,Peter Dandliker,Peter Saradjian,Sam Kattar,Victoria Kutilek

Unbiased Phenotype Detection Using Negative Controls

Antje Janosch,Carolin Kaffka,Marc Bickle

Screening Approaches for Targeting Ribonucleoprotein Complexes: A New Dimension for Drug Discovery

Alessandro Provenzani,Alessandro Quattrone,Chiara Zucal,Denise Sighel,Graziano Lolli,Isabelle Bonomo,Mariachiara Micaelli,Valentina Adami,Vito Giuseppe D’Agostino

A High

Albert Gough,Andreas Vogt,Anthony Schwacha,Emily Tsai,Marilyn Ngo,Mark E. Schurdak,Nick Wechter,Tong Ying Shun

Application of New Cellular and Microphysiological Systems to Drug Metabolism Optimization and Their Positioning Respective to In Silico Tools

Luca Docci,Neil Parrott,Stephan Kr？henbühl,Stephen Fowler

Identification of Novel Phospholipid Transfer Protein Inhibitors by High

Rie Hantani,Tomohiro Sotani,Yoshiji Hantani,Yu Takahashi

Implementation of the NCI

Allen Xinwei Wang,David A. Close,Julie L. Eiseman,Paul A. Johnston,Stanton J. Kochanek,Tongying Shun

Evaluation of Machine Learning Classifiers to Predict Compound Mechanism of Action When Transferred across Distinct Cell Lines

John C. Dawson,Neil O. Carragher,Scott J. Warchal

Identification of an Arginase II Inhibitor via RapidFire Mass Spectrometry Combined with Hydrophilic Interaction Chromatography

Motoaki Kawano,Wataru Asano,Yoshiji Hantani,Yu Takahashi

3D Cell

Erik H. J. Danen,Leo S. Price,Tijmen H. Booij

A General Guide for the Optimization of Enzyme Assay Conditions Using the Design of Experiments Approach

Christos Papaneophytou,Favour Chinyere Onyeogaziri

Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform

Alberto Venturelli,Anabela Cordeiro-da-Silva,Antonio Quotadamo,Bernhard Ellinger,Bethlehem Kebede,Birte Behrens,Bruno dos Santos Pascoalino,Carolina B. Moraes,Cecilia Pozzi,Chiara Borsari,Claudia P. Bertolacini,Deepa Karunakaran,Elisa Uliassi,Flavio Di Pisa,Gesa Witt,Giacomo Landi,Ina P？hner,Jeanette Reinshagen,Jennifer Leu,Joachim Clos,Joanna Panecka-Hofman,José María Alunda,Kyriakos C. Prousis,Lucia Dello Iacono,Lucio H. Freitas-Junior,Maria Kuzikov,Maria Laura Bolognesi,Maria Paola Costi,Markus Wolf,Martina Fenske,María Jesús Corral,Matteo Santucci,Nuno Santarem,Oliver Keminer,Pasquale Linciano,Rebecca C. Wade,Sheraz Gul,Stefania Ferrari,Stefano Mangani,Stephen Wrigley,Theodora Calogeropoulou,Wolfgang Müller

Patient

Dennis J. Colussi,Marlene A. Jacobson

Development of a Selection Method for Discovering Irreversible (Covalent) Binders from a DNA

Christopher B. Phelps,Christopher P. Davie,Ghotas Evindar,Kenneth E. Lind,LaShadric C. Grady,Yun Ding,Zhengrong Zhu

High

Bastian So-Song Schumacher,Holger Erfle,Jürgen Beneke,Manuel Gunkel,Nina Beil,Piotr Wajda,Ruben Bulkescher,Stefan M. Kallenberger,Tautvydas Lisauskas,Vytaute Starkuviene

DNA Switch: Toehold

Akinori Kuzuya,Soo Khim Chan,Theam Soon Lim,Yee Siew Choong

Design of the LifeArc Index Set and Retrospective Review of Its Performance: A Collection for Sharing

Afrah Sattikar,Andy Merritt,Barbara Saxty,Catherine Kettleborough,Kristian Birchall

A Phenotypic Screening Assay Identifies Modulators of Diamond Blackfan Anemia

Abdul Ghani Alattar,Fredrik Ek,Johan Flygare,Jun Chen,Kavitha Siva,Kristmundur Sigmundsson,Marcin Wlodarski,Roger Olsson,Thomas Lundb？ck

Screening Strategies and Methods for Better Off

James J. Lynch,Michael J. Liguori,Mohan Rao,Scott Warder,Terry R. Van Vleet

Drug Efficacy Comparison of 3D Forming and Preforming Sphere Models with a Micropillar and Microwell Chip Platform

Bosung Ku,Dong Woo Lee,Il Doh,Yong-Jun Kwon

TSA

Bin Tean Teh,Ley-Moy Ng,Po-Hsien Lee,Xi Xiao Huang

Perspective on Antibacterial Lead Identification Challenges and the Role of Hypothesis

Cheryl L. Quinn,Jared A. Silverman,Jennifer A. Leeds,Laura L. McDowell,Lynn L. Silver

A Perspective on Extreme Open Science: Companies Sharing Compounds without Restriction

Carrow I. Wells,David H. Drewry,Timothy M. Willson,William J. Zuercher

Development of a High

Ashwini K. Devkota,Eun Jeong Cho,Hou-Fu Guo,John R. Veloria,Jonathan M. Kurie,Kevin N. Dalby

Inexpensive High

Hirofumi Nakano,Hirotatsu Kojima,Kazuo Kumagai,Riyo Maruki Imamura,Takayoshi Okabe,Tetsuo Nagano

Discovery of a Selective Inhibitor for the YEATS Domains of ENL/AF9

Carina Gileadi,Carmen Coxon,Charline Giroud,Gennady Poda,Gillian Farnie,James Bennett,Octovia Monteiro,Oleg Fedorov,Rima Al-awar,Suet Ling Felce,Thomas Christott,Vicki Gamble,Viktor Beke

Development of High

Barbara J. Graves,David J. Bearss,Hariprasad Vankayalapati,Simon L. Currie,Steven L. Warner,Sunil Sharma,Xiaohui Liu

Drug Discovery on Natural Products: From Ion Channels to nAChRs, from Nature to Libraries, from Analytics to Assays

August B. Smit,Govert W. Somsen,Jeroen Kool,Kristina B. M. Still,Reka A. Otvos

The Scripps Molecular Screening Center and Translational Research Institute

Banu Priya Sridharan,Benjamin Cravatt,Hugh Rosen,Louis Scampavia,Patrick R. Griffin,Pierre Baillargeon,Steven Brown,Timothy P. Spicer,Virneliz Fernandez-Vega

Temperature

Adam Zweifach,Xiuyi Alexander Yang

Developing Colorimetric and Luminescence

Ashwini K. Devkota,Eun Jeong Cho,John Veloria,Kevin N. Dalby,Minhye Shin,Shelley M. Payne

Development of a High

Barton E. Slatko,Bo Wu,Catherine Bardelle,Darren Plant,David Murray,Eileen McCall,Helen Plant,Kelly L. Johnston,Kirsty Rich,Lindsey Cantin,Louise Ford,Mark J. Taylor,Mark Wigglesworth,Matthew Collier,Paul Harper,Rachel H. Clare,Roger Clark,Stephen A. Ward

Reviewer List, 2019

null

Identification of Antimalarial Inhibitors Using Late

Donald L. Gardiner,Frank J. Schoenen,Katharine R. Trenholme,Louis Scampavia,Patrick R. Griffin,Peter Chase,Peter Hodder,Sudeshna Roy,Timothy P. Spicer

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