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Archive of "Cancer Biology & Therapy".

ISSN Print: 1538-4047

ISSN Online:

主页: https://www.ncbi.nlm.nih.gov/pmc/journals/1361/

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Enhancing the efficacy of glycolytic blockade in cancer cells via RAD51 inhibition

Bryant R. A. Perkins,Christine Rosales,Derry C. Roopenian,Elise E. Wolf,Grace Stafford,Jane A. Branca,John J. Wilson,Kevin D. Mills,Kin-hoe Chow,Mauro Costa,Muneer G. Hasham,Nathan J. Labrie,Thomas J. Sproule

Next-generation sequencing of prostate cancer: genomic and pathway alterations, potential actionability patterns, and relative rate of use of clinical-grade testing

Brett N. Tomson,Jennifer L. Carter,Razelle Kurzrock,Sadakatsu Ikeda,Sheryl K. Elkin

Adeno-associated virus 2 mediated gene transfer of vascular endothelial growth factor Trap: a new treatment option for glioma

Fabao Gao,Lei Wang,Li Yang,Liqun Zou,Shengnan Zhao,Yakun Zhang

A new look at molecular biology of breast cancer

Chi Ma,Jin-Hee Kim,Manoj Nepal,Peiwen Fei,Ping Fan

A multicenter REtrospective observational study of first-line treatment with PERtuzumab, trastuzumab and taxanes for advanced HER2 positive breast cancer patients. RePer Study

Agnese Latorre,Alain Gelibter,Alessandra Cassano,Andrea Botticelli,Angela Vaccaro,Angelo Fedele Scinto,Antonio Giordano,Carlo Garufi,Clara Natoli,Claudia Omarini,Daniele Santini,Domenico Corsi,Domenico Sergi,Emanuela Magnolfi,Emilio Bria,Enzo Veltri,Ernesto Rossi,Francesco Giotta,Gennaro Ciliberto,Giacomo Barchiesi,Giancarlo Paoletti,Giuseppe Sanguineti,Giuseppe Tonini,Ida Paris,Isabella Sperduti,Jennifer Foglietta,Laura Iezzi,Laura Pizzuti,Loretta D’Onofrio,Luca Moscetti,Lucia Mentuccia,Luciano Mariani,Luigi Di Lauro,Luisa Carbognin,Maddalena Barba,Marcello Maugeri-Saccà,Marco Mazzotta,Maria Agnese Fabbri,Paolo Marchetti,Patrizia Vici,Riccardo Samaritani,Roberta Sarmiento,Rosanna Mirabelli,Ruggero De Maria,Sandro Barni,Silverio Tomao,Teresa Gamucci,Valentina Magri,Vincenzo Graziano

Synergistic effect of resveratrol and HSV-TK/GCV therapy on murine hepatoma cells

Biaoyan Du,Guangxian Zhang,Jianyong Xiao,Kun Wang,Qing Zhao,Xiaodong Liu,Xiaolan Wang,Yingya Wu,Yizhen Ning,Yuhui Tan,Zengqiang Zhao

Discovery and mechanisms of host defense to oncogenesis: targeting the β-defensin-1 peptide as a natural tumor inhibitor

Carrie Q. Sun,Chia-Ling Hsieh,Fei Lian,John A. Petros,Julia R. Dorin,Rebecca S. Arnold,Zhenghong Li

Detecting and phenotyping of aneuploid circulating tumor cells in patients with various malignancies

Liang Cheng,Na Ding,Qian Zhang,Qijun Qian,Shuo Ma,Xiaoxia Zhang,Xinyue Wang,Yongmei Ding,Zenghui Xu,Zhenlong Ye,Zhong Li,Zhuo Chen

Combined α-programmed death-1 monoclonal antibody blockade and fractionated radiation therapy reduces tumor growth in mouse EL4 lymphoma

Bevan Yueh,Haichun Lai,Huanjiao Weng,Huichun Gong,Jianbo Yang,Jiani Xiong,Jinxiang Lin,Jizhen Lin,Luke Morton,Niangmei Cheng,Pan Jiang,Qianqian Xu,Qiong Zhang,Rong Jin,Shubin Fang,Shuchun Lin,Tao Zeng,Xinling Tian,Xiufeng Li,Xiuyun Lin,Yunlu Xu,Zhiwei Chen

Lamc1 promotes the Warburg effect in hepatocellular carcinoma cells by regulating PKM2 expression through AKT pathway

ChengJun Wu,DeBiao Pan,GuanXiong Ye,HaiLin Ye,HeJuan Shen,Jun Wang,ShengQian Xu,Shi Wang,XinMei Wang,Yong Qin

Clinical importance of FANCD2, BRIP1, BRCA1, BRCA2 and FANCF expression in ovarian carcinomas

Agnieszka Dansonka-Mieszkowska,Aneta Balabas,Iwona K. Rzepecka,Joanna Chodzynska,Joanna Moes-Sosnowska,Jolanta Kupryjanczyk,Lukasz M. Szafron,Piotr Sobiczewski,Renata Lotocka

Next-generation sequencing reveals mutational accordance between cell-free DNA from plasma, malignant pleural effusion and ascites and directs targeted therapy in a gastric cancer patient

Baorui Liu,Bo Xu,Dongqin Zhu,Jia Wei,Liang Qi,Shujuan Zhou

Discovery of a novel DNA polymerase inhibitor and characterization of its antiproliferative properties

Bhanvi Mishra,Ernest Y.C. Lee,Hong Zhao,Marietta Y.W.T. Lee,Sufang Zhang,Zbigniew Darzynkiewicz,Zhongtao Zhang

Antitumor effect of curcumin liposome after transcatheter arterial embolization in VX2 rabbits

Chenguang Bai,Feng Dai,Hanzi Xu,Jun Chen,Wei Qiao,Wenrong Shen,Xiaodong Xie,Xiuming Zhang

ELF3 is an antagonist of oncogenic-signalling-induced expression of EMT-TF ZEB1

D Liu,E Bowler,J Song,K Tamai,M Ayati,M Koyuturk,M Ravasz,R Harris,R.M. Ewing,S Bai,X Yuan,Y Skomorovska,Y Wang,Z Wang

PDGFRα expression as a novel therapeutic marker in well-differentiated neuroendocrine tumors

Antonia Ignazzi,Elisabetta Cavalcanti,Francesco De Michele,Maria Lucia Caruso

Predictive and prognostic value of PDL1 protein expression in breast cancer patients in neoadjuvant setting

Jing Peng,Jinglu Lu,Jinsong Lu,Lei Zhang,Liheng Zhou,Shuguang Xu,Wenjin Yin,Yan Wang,Yanpin Lin,Ziping Wu

Combined inhibition of the PI3K/mTOR/MEK pathway induces Bim/Mcl-1-regulated apoptosis in pancreatic cancer cells

Elaina N. Maginn,Euan A. Stronach,Hani Gabra,Harpreet S. Wasan,Rajpal S. Burmi

Serine protease modulation of Dependence Receptors and EMT protein expression

Caroline M. Forrest,Kara McNair,L. Gail Darlington,Maria C. J. Vincenten,Trevor W. Stone

Metastatic colon adenocarcinoma has a significantly elevated expression of IL-10 compared with primary colon adenocarcinoma tumors

Abigail M. Felsted,Kim L. O'Neill,Michelle H. Townsend,Richard A. Robison,Stephen R. Piccolo

Animal models for studying tumor microenvironment (TME) and resistance to lymphocytic infiltration

Guy Perkins,Ryuji Yamaguchi

JAK2 V617F mutation in plasma cell-free DNA preceding clinically overt myelofibrosis: Implications for early diagnosis

Huan-You Wang,Jonathan H. Lin,Michael Y. Choi,Razelle Kurzrock,Richard B. Lanman,Shumei Kato

A new mutation of the CDH1 gene in a patient with an aggressive signet-ring cell carcinoma of the stomach

Angela Buonadonna,Antonio Cossu,Davide Adriano Santeufemia,Gianmaria Miolo,Giuseppe Corona,Lara Alessandrini,Laura Caggiari,Mariangela De Zorzi,Renato Cannizzaro,Valli De Re,Vincenzo Canzonieri

Induction of anaplastic lymphoma kinase (ALK) as a novel mechanism of EGFR inhibitor resistance in head and neck squamous cell carcinoma patient-derived models

Aletha Lesch,Ashley Barling,Christina Zheng,Daniel Clayburgh,Gabrielle Choonoo,Jeffrey W. Tyner,Sara A. Courtneidge,Shannon K. McWeeney,Sophia Jeng,Toni M. West,Xiaoming Ouyang

Molecular drivers of metastatic castrate-resistant prostate cancer: New roads to resistance

Douglas K. Price,Phoebe A. Huang,William D. Figg

A retrospective case study of sunitinib treatment in three patients with Von Hippel-Lindau disease

Dali Tong,Gang Yuan,Gaolei Liu,Jun Jiang,Jun Zhang,Lin-ang Wang,Luofu Wang,Qiuli Liu,Rongrong Chen,Weihua Lan,Xin Yi,Yanfang Guan,Yao Zhang,Yuting Yi

A novel BRCA2 mutation in prostate cancer sensitive to combined radiotherapy and androgen deprivation therapy

Dali Tong,Dianzheng Zhang,Gang Yuan,Gaolei Liu,Jin Ye,Jing Xu,Jun Jiang,Jun Zhang,Linang Wang,Peng Wang,Qiuli Liu,Rongrong Chen,Xin Yi,Xingxia Yang,Yanfang Guan,Yao Zhang,Yuting Yi

Focal adhesion kinase a potential therapeutic target for pancreatic cancer and malignant pleural mesothelioma

Bolot Mambetsariev,Garima Kaushik,Hedy L. Kindler,Immanuel Dhanasingh,Jacob J. Riehm,Jiale Wang,Mohd W. Nasser,Moorthy P. Ponnusamy,Parthasarathy Seshacharyulu,Prakash Kulkarni,Rajani Kanteti,Ravi Salgia,Surinder K. Batra,Tamara Mirzapoiazova

MicroRNA-326 sensitizes human glioblastoma cells to curcumin via the SHH/GLI1 signaling pathway

Bo Han,Chuanlu Jiang,Daming Liu,Dongbo Yang,Feng Wang,Hui Chen,Shi Yin,Wenzhong Du,Xing Liu,Xiuwei Zhai,Yuqiong Cui

The levels of mutant K-RAS and mutant N-RAS are rapidly reduced in a Beclin1 / ATG5 -dependent fashion by the irreversible ERBB1/2/4 inhibitor neratinib

Alshad S. Lalani,Andrew Poklepovic,Cindy Sander,Francesca Avogadri-Connors,Jane L. Roberts,John Kirkwood,Laurence Booth,Paul Dent,Richard E. Cutler Jr

Lenalidomide combined with R-GDP in a patient with refractory CD5-positive diffuse large B-cell lymphoma: A promising response and review

Chunfeng Sun,Hongming Huang,Wenyu Shi,Xinfeng Wang,Yaping Zhang,Yifei Liu

Nucleoside diphosphate kinase B promotes osteosarcoma proliferation through c-Myc

Dongdong Cheng,Qingcheng Yang,Shijie Li,Ting Yuan,Tu Hu

In Vitro and In Vivo evaluation of a novel folate-targeted theranostic nanoemulsion of docetaxel for imaging and improved anticancer activity against ovarian cancers

Abbegail H. Nack,Aleksandr Piroyan,Allison B. Morse,April L. Solon,Barbara Davis,Collete Bora,Corin A. Galati,Denise C. Connolly,Katie M. Candiloro,Marisa A. Maglaty,Niravkumar R. Patel,Samuel Litwin,Shane W. O'Brien,Srinivas Ganta,Timothy P. Coleman

Efficacy generated by afatinib in a lung adenocarcinoma patient harboring HER2 S310Y mutation

Guanggui Ding,Jian Wang,Jing Liu,Lin Yang,Lu Zhang,Peikun Ding,Tengfei Zhang,Yuxin Wen

The irreversible ERBB1/2/4 inhibitor neratinib interacts with the PARP1 inhibitor niraparib to kill ovarian cancer cells

Alshad S. Lalani,Andrew Poklepovic,Francesca Avogadri-Connors,Jane L. Roberts,Laurence Booth,Paul Dent,Peter Samuel,Richard E. Cutler

Breast cancer in an 18-year-old female: A fatal case report and literature review

Andrzej Semczuk,Jacek Wojciechowicz,Maciej Jó？wik,Magdalena Garbowicz,Magdalena Gogiel-Shields,Marcin Jó？wik,Mark Klukowski,Marta Ku？-S？owińska,Renata Posmyk

LncRNA ADPGK-AS1 promotes pancreatic cancer progression through activating ZEB1-mediated epithelial–mesenchymal transition

Hongbo Wang,Mingbao Zhang,Sen Lin,Shuang Guo,Suzhen Song,Teng Wang,Weihua Yu

UFH-001 cells: A novel triple negative, CAIX-positive, human breast cancer model system

Christopher J. Frost,Coy D. Heldermon,Lingbao Ai,Mam Y. Mboge,Robert McKenna,Susan C. Frost,Zhijuan Chen

PI3K/AKT/mTOR pathway inhibitors inhibit the growth of melanoma cells with mTOR H2189Y mutations in vitro

Chuanliang Cui,Huan Tang,Huan Yu,Jiayi Yu,Jie Dai,Jun Guo,Junya Yan,Lu Si,Meng Ma,Tianxiao Xu,Xiaowen Wu,Xinan Sheng,Yan Kong,Zhihong Chi

CA125 suppresses amatuximab immune-effector function and elevated serum levels are associated with reduced clinical response in first line mesothelioma patients

Charles Schweizer,Elizabeth B. Somers,Erin N. Ross,J. Bradford Kline,Luigi Grasso,Nicholas C. Nicolaides,Raffit Hassan,Shawn Fernando,Wenquan Wang

A fragment of SPARC reflecting increased collagen affinity shows pathological relevance in lung cancer – implications of a new collagen chaperone function of SPARC

D.J. Leeming,M. A. Karsdal,N. Willumsen,S. Brix,S. Sun,S.N. Kehlet,T. Manon-Jensen

Liquid biopsy of bile for the molecular diagnosis of gallbladder cancer

Chihiro Dohi,Hideaki Kinugasa,Hironari Kato,Hiroshi Matsushita,Hiroyuki Okada,Kazuhiro Nouso,Kazuyuki Matsumoto,Soichiro Ako

Valproate augments Niraparib killing of tumor cells

Andrew Poklepovic,Jane L. Roberts,Laurence Booth,Paul Dent,Rumeesa Rais

Autophagy as a mechanism of Apo2L/TRAIL resistance

Alexandru Almasan,Arishya Sharma

Unusually long-term responses to vemurafenib in BRAF V600E mutated colon and thyroid cancers followed by the development of rare RAS activating mutations

Eliya Shachar,Ethan Sokol,Garrett Frampton,Ido Wolf,Ravit Geva,Sharon Pelles,Tali Ofir Dovrat

Early brain metastasis of advanced gastric cancer with a pathological complete response to neoadjuvant chemotherapy followed by surgery: A case report and literature review

Chengcheng Fan,Hong Ge,Hui Luo,Jiangong Zhang,Liangqun Peng,Nan Wang,Xiaoli Zheng,Yanan Sun

Drivers of treatment patterns in patients with chronic lymphocytic leukemia stopping ibrutinib or idelalisib therapies

Anthony R. Mato,Danielle M. Brander,Emi Terasawa,Geneviève Gauthier,Jennifer C. Samp

Turning cancer's metabolic plasticity into fragility- an evolving paradigm

Shanmugasundaram Ganapathy-Kanniappan

Molecular alterations associated with chronic exposure to cigarette smoke and chewing tobacco in normal oral keratinocytes

Aditi Chatterjee,Anjali Kumari,Ankit P. Jain,Arati Khanna-Gupta,Bipin Nair,David Sidransky,Harsha Gowda,Joseph Califano,Karunakaran Coral,Keshava K. Datta,Kiran K. Mangalaparthi,Krishna Patel,Malini Manoharan,Pavithra Rajagopalan,Premendu P. Mathur,Ravi Gupta,Rohit Gupta,Sakthivel Murugan,T. S. Keshava Prasad,Tejaswini Subbannayya,Vishalakshi Nanjappa

HPV epigenetic mechanisms related to Oropharyngeal and Cervix cancers

Antonia Feola,Antonio Giordano,Camilla Siciliano,Francesco De Francesco,Giancarlo Giovane,Luigi Califano,Marina Di Domenico,Maurizio Romano,Rosamaria Iorio,Soumaya Kouidhi

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