%0 Journal Article
%T Association between Vascular Calcification and Bone Mineral Density in Chronic Hemodialysis Patients: A Single Moroccan Center Experience
%A Majdouline Errihani
%A Kawtar Hassani
%A Aya Sobhi
%A Sanaa Benbria
%A Yassir Zajjari
%A Driss Elkabbaj
%J Open Access Library Journal
%V 12
%N 1
%P 1-9
%@ 2333-9721
%D 2025
%I Open Access Library
%R 10.4236/oalib.1112842
%X <strong>Introduction</strong>: Chronic kidney disease-mineral and bone disorders (CKD-MBD) are characterized by generalized vascular calcification (VC) and impaired bone health. We aimed to investigate the relationship between VC and bone mineral density (BMD) in chronic hemodialysis patients. <strong>Methods</strong>: A cross-sectional study included 40 chronic hemodialysis patients for at least 6 months. For the assessment of VC, abdominal aorta lateral lumbar X-rays were used, and for the analysis of bone mineral density, dual-energy X-ray absorptiometry (DXA) at the lumbar spine (LS) and femoral neck (FN) was provided. Results: Forty patients were included; the average age was 59 ¡À 16 years, 47% were women, and the median of hemodialysis duration was 54 months. The prevalence of AAC was 57.5%; and the median AAC score was 3 [0.10]. The prevalence of osteoporosis at the lumbar spine was 27.5%, while at the femoral neck, it was 32.5%. The mean BMD at the lumbar spine was 0.999 <span style="text-wrap-mode:wrap;">¡À</span> 0.213; and at the femoral neck, it was 0.814 <span style="text-wrap-mode:wrap;">¡À</span> 0.239. In the correlation analysis, there was a significant association between AAC and BMD; ACC was inversely correlated with BMD of the spine (r = -0.368, p = 0.019) and femoral neck (r = -0.578, p £¼ 0.001). In linear regression analysis, with AAC as the dependent variable, there was a statistically significant negative relationship with BMD of the spine (p = 0.024), and BMD of the femoral neck (p = 0.002). <strong>Conclusion</strong>: Our study demonstrated that the presence of CV reduces BMD in hemodialysis patients; this implies the need for early diagnosis and optimal management of CKD-MBD. We believe that the results of our study will help in the planning of future research, as they also confirm the existence of the vascular-bone axis.
%K Bone Mineral Density
%K Hemodialysis
%K Vascular Calcification
%U http://www.oalib.com/paper/6847572